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product-image-AAA227398_STRUCTURE13.gif Structure (Peripheral Myelin P0 Protein (180-199), mouse, CAS 147450-30-4)

C22 dihydro 1-Deoxyceramide (m18:0/22:0) Biochemical

C22 dihydro 1-Deoxyceramide (m18:0/22:0)

Purity
98%
Synonyms
C22 dihydro 1-Deoxyceramide (m18:0/22:0); N/A; C22 dihydro 1-Deoxyceramide (m18:0/22:0) biochemical
Ordering
Purity/Purification
98%
Solubility
Ethanol: 30 mg/mL

DMF: 20 mg/mL

DMSO: 20 mg/mL

Ethanol:PBS (pH 7.2)(1:1): 0.5 mg/mL
<1mg/ml refers to the product slightly soluble or insoluble
Preparation and Storage
Powder: -20 degree C for 3 years
In solvent: -80 degree C for 2 years

Structure

(Peripheral Myelin P0 Protein (180-199), mouse, CAS 147450-30-4)

product-image-AAA227398_STRUCTURE13.gif Structure (Peripheral Myelin P0 Protein (180-199), mouse, CAS 147450-30-4)

Structure

(Peripheral Myelin P0 Protein (180-199), mouse, CAS 147450-30-4)

product-image-AAA227398_STRUCTURE15.gif Structure (Peripheral Myelin P0 Protein (180-199), mouse, CAS 147450-30-4)
Related Product Information for C22 dihydro 1-Deoxyceramide (m18:0/22:0) biochemical
C22 dihydro 1-Deoxyceramide (m18:0/22:0) is a very long-chain atypical ceramide containing a 1-deoxysphinganine backbone. 1-Deoxysphingolipids are formed when serine palmitoyltransferase condenses palmitoyl-CoA with alanine instead of serine during sphingolipid synthesis.1,2 C22 dihydro 1-Deoxyceramide (m18:0/22:0) has been found in mouse embryonic fibroblasts (MEFs) following application of 1-deoxysphinganine alkyne or 1-deoxysphinganine-d3.3 It has also been found as the most prevalent dihydro deoxyceramide species in mouse brain, spinal cord, and sciatic nerve at one, three, and six months of age.4
References
1. Lei Bao, et al. The critical role of IL-12p40 in initiating, enhancing, and perpetuating pathogenic events in murine experimental autoimmune neuritis. Brain Pathol. 2002 Oct;12(4):420-9.
2. L P Zou, et al. P0 protein peptide 180-199 together with pertussis toxin induces experimental autoimmune neuritis in resistant C57BL/6 mice. J Neurosci Res. 2000 Dec 1;62(5):717-21.

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Product Notes

The C22 dihydro 1-Deoxyceramide (m18:0/22:0) (Catalog #AAA227398) is a Biochemical and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "C22 dihydro 1-Deoxyceramide (m18:0/22:0), Biochemical" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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