Structure
(MK-5204, CAS 1207751-75-4)
Caloxin 2A1 TFA Biochemical
Caloxin 2A1 TFA
Purity
98%
Synonyms
Caloxin 2A1 TFA; N/A; Caloxin 2A1 TFA biochemical
Purity/Purification
98%
Solubility
DMSO: 100 mg/mL (62.79 mM),
Need ultrasonic
<1mg/ml refers to the product slightly soluble or insoluble
Need ultrasonic
<1mg/ml refers to the product slightly soluble or insoluble
In vitro
Caloxin 2A1 TFA inhibits Ca2+-Mg2+-ATPase in human erythrocyte leaky ghosts, but it does not affect basal Mg2+-ATPase or Na+-K+-ATPase in the ghosts or Ca2+-Mg2+-ATPase in the skeletal muscle sarcoplasmic reticulum. Caloxin 2A1 TFA also inhibits Ca2+-dependent formation of the 140-kDa acid-stable acylphosphate[1].Caloxin 2A1 TFA increases airway smooth muscle cells (ASMCs) apoptosis[2].
Preparation and Storage
Powder: -20 degree C for 3 years
In solvent: -80 degree C for 2 years
In solvent: -80 degree C for 2 years
Structure
(MK-5204, CAS 1207751-75-4)
Structure
(MK-5204, CAS 1207751-75-4)
Structure
(MK-5204, CAS 1207751-75-4)
Structure
(MK-5204, CAS 1207751-75-4)
Related Product Information for Caloxin 2A1 TFA biochemical
Caloxin 2A1 TFA is an extracellular plasma membrane Ca2+-ATPase (PMCA) peptide inhibitor. Caloxin 2A1 TFA does not affect basal Mg2+-ATPase or Na+-K+-ATPase[1].
References
1. Apgar JM, et al. MK-5204: An orally active beta-1,3-glucan synthesis inhibitor. Bioorg Med Chem Lett. 2020 Sep 1;30(17):127357.
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Product Notes
The Caloxin 2A1 TFA (Catalog #AAA227087) is a Biochemical and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Caloxin 2A1 TFA, Biochemical" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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