Purity/Purification
98%
CAS
1431945-95-7
Solubility
<1mg/ml refers to the product slightly soluble or insoluble
In vitro
FATP1-IN-1 (p.o.; 10 mg/kg) treatment shows the C max, AUC and T max were 5.5 ug/mL, 36 ug h/mL and 0.33 hours, respectively, and exceeds the mouse IC 50 value of 0.22 uM without considering plasma protein binding. Animal Model: Mouse plasma[1]. Dosage: 10 mg/kg. Administration: P.o. Result: The C max, AUC and T max were 5.5 ug/mL, 36 ug h/mL and 0.33 hours, respectively.
Preparation and Storage
Powder: -20 degree C for 3 years
In solvent: -80 degree C for 2 years
In solvent: -80 degree C for 2 years
Related Product Information for FATP1-IN-1 biochemical
FATP1-IN-1 is a fatty acid transport protein 1 (FATP1) inhibitor. FATP1-IN-1 is an inhibition of recombinant human or mouse acyl-CoA synthetase activity of FATP1, with the IC 50 values of 0.046 uM or 0.60 uM, respectively.
References
1. Morozumi N, et al. ASB20123: A novel C-type natriuretic peptide derivative for treatment of growth failure and dwarfism. PLoS One. 2019 Feb 22;14(2):e0212680.
2. Mazarati AM, et al. ANP(1-28), BNP(1-32) and CNP(1-22) increase the severity of picrotoxin-kindled seizure syndrome in rats. Life Sci. 1993;52(3):PL19-24.
2. Mazarati AM, et al. ANP(1-28), BNP(1-32) and CNP(1-22) increase the severity of picrotoxin-kindled seizure syndrome in rats. Life Sci. 1993;52(3):PL19-24.
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Product Notes
The FATP1-IN-1 (Catalog #AAA227707) is a Biochemical and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "FATP1-IN-1, Biochemical" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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