Structure
(Gosferol, CAS 37551-62-5)
HJC0416 hydrochloride Biochemical | HJC0416 biochemical
HJC0416 hydrochloride
Purity
98%
Synonyms
HJC0416 hydrochloride; N/A; HJC0416 biochemical
Purity/Purification
98%
CAS
2415263-08-8
Solubility
<1mg/ml refers to the product slightly soluble or insoluble
In vitro
HJC0416 hydrochloride (intraperitoneal injection; 10 mg/kg; 7 days) shows a 67% decrease of tumor volume as compared to the control mice. Similarly, HJC0416 hydrochloride (oral administration; 100 mg/kg; 14 days) also significantly reduces tumor volume at a dose of 100 mg/kg by 46%. The i.p. route appeared to have a better reduction of tumor volume. It is also noteworthy that HJC0416 does not show significant signs of toxicity at a dose of 100 mg/kg[1]. Animal Model: Mice with MDA-MB-231 cells[1]. Dosage: 10 mg/kg (i.p.); 100 mg/kg (oral). Administration: intraperitoneal injection, 7 days; oral administration, 14 days. Result: Exhibited antitumor effects in the MDA-MB-231 triple-negative breast cancer murine xenograft model.
Preparation and Storage
Powder: -20 degree C for 3 years
In solvent: -80 degree C for 2 years
In solvent: -80 degree C for 2 years
Structure
(Gosferol, CAS 37551-62-5)
Structure
(Gosferol, CAS 37551-62-5)
Structure
(Gosferol, CAS 37551-62-5)
Structure
(Gosferol, CAS 37551-62-5)
Related Product Information for HJC0416 biochemical
HJC0416 hydrochloride is a potent and orally active STAT3 inhibitor with an enhanced anticancer profile than Stattic (HY-13818). HJC0416 hydrochloride is a promising anti-cancer agent for breast cancer study.
References
1. Abyshev, A.Z., et al. Gosferol — A new furocoumarin from the roots of Prangos ferulacea. Chem Nat Compd 8, 43-47 (1972).
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Product Notes
The HJC0416 (Catalog #AAA228420) is a Biochemical and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "HJC0416 hydrochloride, Biochemical" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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