Structure
(ARN19689, CAS 2320521-34-2)
Xanthine amine congener dihydrochloride Biochemical
Xanthine amine congener dihydrochloride
Purity
98%
Synonyms
Xanthine amine congener dihydrochloride; N/A; Xanthine amine congener dihydrochloride biochemical
Purity/Purification
98%
CAS
1962928-23-9
Targets&IC50
adenosine A1 receptor:1.8 nM (IC50), Adenosine A2 receptor:114 nM (IC50)
Solubility
<1mg/ml refers to the product slightly soluble or insoluble
In vitro
Xanthine amine congener dihydrochloride is more potent as a convulsant than either caffeine or theophyllin in infusion studies at the dosage 39.8mg/kg. XAC has no effects by administering the drug via an i.p. injection, the seizure threshold 1000 mg/kg[1]. Animal Model: Mice[1]. Dosage: 39.8mg/kg. Administration: Infusion injection; single dose. Result: Acted as a convulsant agent than either caffeine or theophyllin.
Preparation and Storage
Powder: -20 degree C for 3 years
In solvent: -80 degree C for 2 years
In solvent: -80 degree C for 2 years
Structure
(ARN19689, CAS 2320521-34-2)
Structure
(ARN19689, CAS 2320521-34-2)
Structure
(ARN19689, CAS 2320521-34-2)
Structure
(ARN19689, CAS 2320521-34-2)
Related Product Information for Xanthine amine congener dihydrochloride biochemical
Xanthine amine congener dihydrochloride (XAC dihydrochloride) is a potent Adenosine A1 receptor and A2 receptor antagonist with IC 50 values of 1.8 and 114 nM, respectively. Xanthine amine congener acts as a convulsant agent in mice model.
References
1. Di Fruscia P, et al. Discovery and SAR Evolution of Pyrazole Azabicyclo[3.2.1]octane Sulfonamides as a Novel Class of Non-Covalent N-Acylethanolamine-Hydrolyzing Acid Amidase (NAAA) Inhibitors for Oral Administration. J Med Chem. 2021 Sep 23;64(18):13327-13355.
Similar Products
Product Notes
The Xanthine amine congener dihydrochloride (Catalog #AAA228020) is a Biochemical and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Xanthine amine congener dihydrochloride, Biochemical" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.