Syncytin 1 Blocking Peptide | ERVW-1 blocking peptide
Syncytin 1 Blocking Peptide
Gene Names
ERVW-1; ENV; ENVW; HERVW; ERVWE1; HERV7Q; HERV-7q; HERVWENV; HERV-W-ENV
Applications
Immunocompetition, Immunodepletion
Synonyms
Syncytin 1; N/A; Syncytin 1 Blocking Peptide; Endogenous retrovirus group W member 1 antibody; env antibody; Env-W antibody; Envelope polyprotein gPr73 antibody; Enverin antibody; ERVW antibody; ERVW-1 antibody; Gp24 antibody; Gp50 antibody; HERV-7q Envelope protein antibody; HERV-W envelope protein antibody; HERVW antibody; SU antibody; Syncytin 1 antibody; TM antibody; Transmembrane protein antibody; ERVW-1 blocking peptide
Form/Format
Antigenic Blocking Peptide
Sequence Length
538
Applicable Applications for ERVW-1 blocking peptide
Immunocompetition, Immunodepletion
Preparation and Storage
Store at -20 degree C for long term storage.
Related Product Information for ERVW-1 blocking peptide
Overview: This endogenous retroviral envelope protein has retained its original fusogenic properties and participates in trophoblast fusion and the formation of a syncytium during placenta morphogenesis. May induce fusion through binding of SLC1A4 and SLC1A5 (PubMed:10708449, PubMed:12050356, PubMed:23492904).3 Publications
Endogenous envelope proteins may have kept, lost or modified their original function during evolution.
Peptide Description: Synthetic peptide taken within amino acid region 480-538 on human Syncytin-1 protein.
Structure: The cytoplasmic region is essential for the fusiogenic function. The 17 amino acids long immunosuppressive region is present in many retroviral envelope proteins. Synthetic peptides derived from this relatively conserved sequence inhibit immune function in vitro and in vivo.
Expression: Expressed at higher level in placental syncytiotrophoblast. Expressed at intermediate level in testis. Seems also to be found at low level in adrenal tissue, bone marrow, breast, colon, kidney, ovary, prostate, skin, spleen, thymus, thyroid, brain and trachea. Both mRNA and protein levels are significantly increased in the brain of individuals with multiple sclerosis, particularly in astrocytes and microglia.
Endogenous envelope proteins may have kept, lost or modified their original function during evolution.
Peptide Description: Synthetic peptide taken within amino acid region 480-538 on human Syncytin-1 protein.
Structure: The cytoplasmic region is essential for the fusiogenic function. The 17 amino acids long immunosuppressive region is present in many retroviral envelope proteins. Synthetic peptides derived from this relatively conserved sequence inhibit immune function in vitro and in vivo.
Expression: Expressed at higher level in placental syncytiotrophoblast. Expressed at intermediate level in testis. Seems also to be found at low level in adrenal tissue, bone marrow, breast, colon, kidney, ovary, prostate, skin, spleen, thymus, thyroid, brain and trachea. Both mRNA and protein levels are significantly increased in the brain of individuals with multiple sclerosis, particularly in astrocytes and microglia.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
NCBI Official Full Name
syncytin-1
NCBI Official Synonym Full Names
endogenous retrovirus group W member 1, envelope
NCBI Official Symbol
ERVW-1
NCBI Official Synonym Symbols
ENV; ENVW; HERVW; ERVWE1; HERV7Q; HERV-7q; HERVWENV; HERV-W-ENV
NCBI Protein Information
syncytin-1
UniProt Protein Name
Syncytin-1
UniProt Gene Name
ERVW-1
UniProt Synonym Gene Names
ERVWE1; SU; TM
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Product Notes
The ERVW-1 ervw-1 (Catalog #AAA226377) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's Syncytin 1 can be used in a range of immunoassay formats including, but not limited to, Immunocompetition, Immunodepletion. Researchers should empirically determine the suitability of the ERVW-1 ervw-1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Syncytin 1, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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