Application Data
Cadherin-10/CDH10 Recombinant Protein | CDH10 recombinant protein
Recombinant Human Cadherin-10/CDH10 Protein (His Tag), HPLC-verified
Reactivity
Human
Purity
>= 90% as determined by SDS-PAGE. >= 95% as determined by SEC-HPLC.
Synonyms
Cadherin-10/CDH10; N/A; Recombinant Human Cadherin-10/CDH10 Protein (His Tag), HPLC-verified; Human CDH10 Protein (His Tag); CDH10 recombinant protein
Host
HEK293 Cells
Reactivity
Human
Purity/Purification
>= 90% as determined by SDS-PAGE. >= 95% as determined by SEC-HPLC.
Form/Format
Lyophilized from sterile 50 mM Tris, 100 mM NaCl, 3 mM CaCl2, 10% Glycerol, 0.1 M Arg, pH 8.0. Normally 5%-8% trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Sequence
Gly55-Ala613
Tag
C-His
Predicted N Terminal
Gly 55
Endotoxin
< 1.0 EU perug of the protein as determined by the LAL method
Protein Construction
A DNA sequence encoding the Human CDH10 (NP_006718)(Gly55-Ala613) was expressed with a polyhistidine tag at the C-terminus.
Preparation and Storage
Samples are stable for up to twelve months from date of receipt at -20 degree C to -80 degree C. Store it under sterile conditions at -20 degree C to -80 degree C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Application Data
Application Data
Application Data
Application Data
Related Product Information for CDH10 recombinant protein
Cadherin 10 (CDH10) is a type II cadherin predominantly expressed in the brain, putatively involved in axon outgrowth and guidance. Also known to mediate calcium-dependent cell-cell adhesion and maintain the correct balance between excitation and inhibition in neuronal dendrites., CDH 10 has a large N-terminal extracellular domain (containing 5 cadherin motif subdomains which appear to determine the specificity of the protein's homophilic cell adhesion activity), a single membrane-spanning domain, and a small, conserved C-terminal cytoplasmic domain. CDH10 spans 157.7kb on chromosome 5 and produces two transcript variants. Mutations and loss of expression of this protein have been observed in multiple cancer types, including gastric, colorectal, pancreatic, endometrial and lung. Genetic variations nearby the CDH10 genetic region have been associated with autism.
References
1. Smit. KR. e. al. Cadherin-1. Maintain. Excitatory/Inhibitor. Rati. throug. Interaction. wit. Synapti. Proteins. . Neurosci. 2017. doi. 10.1523/JNEUROSCI.1153-17.2017. 2. Jinawat. N. e. al. Alteration. o. typ. I. classica. cadherin. cadherin-1. (CDH10). i. associate. wit. pancreati. ducta. adenocarcinomas. Gene. Chromosome. Cancer. 2017. doi. 10.1002/gcc.22447. 3. Casciell. F. e. al. G9a-mediate. repressio. o. CDH1. i. hypoxi. enhance. breas. tumou. cel. motilit. an. associate. wit. poo. surviva. outcome. Theranostics. 2020. doi. 10.7150/thno.41453.
NCBI and Uniprot Product Information
Molecular Weight
The recombinant Human CDH10 consisting of 570 amino acids and has a calculated molecular mass of 63.66 kDa. As a result of glycosylation, the recombinant protein migrates as an approximately 80.6 kDa protein in SDS-PAGE under reducing conditions.
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Product Notes
The CDH10 (Catalog #AAA259304) is a Recombinant Protein produced from HEK293 Cells and is intended for research purposes only. The product is available for immediate purchase. The Recombinant Human Cadherin-10/CDH10 Protein (His Tag), HPLC-verified reacts with Human and may cross-react with other species as described in the data sheet. The amino acid sequence is listed below: Gly55-Ala6 13. It is sometimes possible for the material contained within the vial of "Cadherin-10/CDH10, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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