SDS-PAGE
Calcitonin gene-related peptide 1 Recombinant Protein | CALCA recombinant protein
Recombinant Human Calcitonin gene-related peptide 1
Gene Names
CALCA; CT; KC; PCT; CGRP; CALC1; CGRP1; CGRP-I
Purity
Greater than 90% as determined by SDS-PAGE.
Synonyms
Calcitonin gene-related peptide 1; N/A; Recombinant Human Calcitonin gene-related peptide 1; Alpha-type CGRP; Calcitonin gene-related peptide I; CGRP-I; CALCA recombinant protein
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater than 90% as determined by SDS-PAGE.
Form/Format
Liquid or Lyophilized powder
If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8
If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8
Sequence Positions
83-118aa; Partial
Sequence
ACDTATCVTHRLAGLLSRSGGVVKNNFVPTNVGSKA
Production Note
Special Offer: The E Coli host-expressed protein is manufactured from a stock plasmid containing the protein gene. E Colihost-expressed protein is stocked in different unit sizes ranging from as small as 10 ug to as large as 1 mg. Bulk inventory is also available. The E Coli host-expressed protein has been ordered over and over again by researchers and has stood the test of time as both a robust protein and important target for the research community. It is part of our new program to make our most popular protein targets and corresponding hosts available in expanded unit sizes and with a quick processing time. Select E Coli host-expressed protein for the fastest delivery among all hosts. Please contact our or email to for more details.
Preparation and Storage
Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.
SDS-PAGE
SDS-PAGE
Related Product Information for CALCA recombinant protein
CGRP induces vasodilation. It dilates a variety of vessels including the coronary, cerebral and systemic vasculature. Its abundance in the CNS also points toward a neurotransmitter or neuromodulator role. It also elevates platelet cAMP.
Product Categories/Family for CALCA recombinant protein
References
Alternative RNA processing events in human calcitonin/calcitonin gene-related peptide gene expression.Jonas V., Lin C.R., Kawashima E., Semon D., Swanson L.W., Mermod J.-J., Evans R.M., Rosenfeld M.G.Proc. Natl. Acad. Sci. U.S.A. 82:1994-1998(1985) Structure and methylation of the human calcitonin/alpha-CGRP gene.Broad P.M., Symes A.J., Thakker R.V., Craig R.K.Nucleic Acids Res. 17:6999-7011(1989) Human chromosome 11 DNA sequence and analysis including novel gene identification.Taylor T.D., Noguchi H., Totoki Y., Toyoda A., Kuroki Y., Dewar K., Lloyd C., Itoh T., Takeda T., Kim D.-W., She X., Barlow K.F., Bloom T., Bruford E., Chang J.L., Cuomo C.A., Eichler E., FitzGerald M.G., Jaffe D.B., LaButti K., Nicol R., Park H.-S., Seaman C., Sougnez C., Yang X., Zimmer A.R., Zody M.C., Birren B.W., Nusbaum C., Fujiyama A., Hattori M., Rogers J., Lander E.S., Sakaki Y.Nature 440:497-500(2006) Structure and expression of a gene encoding human calcitonin and calcitonin gene related peptide.Nelkin B.D., Rosenfeld K.I., de Bustros A., Leong S.S., Roos B.A., Baylin S.B.Biochem. Biophys. Res. Commun. 123:648-655(1984) Expression of the human calcitonin/CGRP gene in lung and thyroid carcinoma.Edbrooke M.R., Parker D., McVey J.H., Riley J.H., Sorenson G.D., Pettengill O.S., Craig R.K.EMBO J. 4:715-724(1985) Calcitonin gene related peptide coding sequence is conserved in the human genome and is expressed in medullary thyroid carcinoma.Steenbergh P.H., Hoppener J.W., Zandberg J., de Ven W.J., Jansz H.S., Lips C.J.J. Clin. Endocrinol. Metab. 59:358-360(1984) Expression and function of the human calcitonin/alpha-CGRP gene in health and disease.Craig R.K., Riley J.H., Edbrooke M.R., Broad P.M., Foord S.M., Al-Kazwini S.J., Holman J.J., Marshall I.Biochem. Soc. Symp. 52:91-105(1986) Isolation and characterization of human calcitonin gene-related peptide.Morris H.R., Panico M., Etienne T., Tippins J., Girgis S.I., McIntyre I.Nature 308:746-748(1984) Identification in the human central nervous system, pituitary, and thyroid of a novel calcitonin gene-related peptide, and partial amino acid sequence in the spinal cord.Petermann J.B., Born W., Chang J.Y., Fischer J.A.J. Biol. Chem. 262:542-545(1987) Isolation and characterization of peptides which act on rat platelets, from a pheochromocytoma.Kitamura K., Kangawa K., Kawamoto M., Ichiki Y., Matsuo H., Eto T.Biochem. Biophys. Res. Commun. 185:134-141(1992) Solution structure of human calcitonin gene-related peptide by 1H NMR and distance geometry with restrained molecular dynamics.Breeze A.L., Harvey T.S., Bazzo R., Campbell I.D.Biochemistry 30:575-582(1991) Solution structures of calcitonin-gene-related-peptide analogues of calcitonin-gene-related peptide and amylin.Hubbard J.A.M., Martin S.R., Chaplin L.C., Bose C., Kelly S.M., Price N.C.Biochem. J. 275:785-788(1991)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
30.6 kDa
NCBI Official Full Name
calcitonin gene-related peptide 1 isoform alpha-CGRP preproprotein
NCBI Official Synonym Full Names
calcitonin-related polypeptide alpha
NCBI Official Symbol
CALCA
NCBI Official Synonym Symbols
CT; KC; PCT; CGRP; CALC1; CGRP1; CGRP-I
NCBI Protein Information
calcitonin; calcitonin gene-related peptide 1
UniProt Protein Name
Calcitonin gene-related peptide 1
UniProt Gene Name
CALCA
UniProt Synonym Gene Names
CALC1; CGRP-I
UniProt Entry Name
CALCA_HUMAN
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Product Notes
The CALCA calca (Catalog #AAA116214) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 83-118aa; Partial. The amino acid sequence is listed below: ACDTATCVTH RLAGLLSRSG GVVKNNFVPT NVGSKA. It is sometimes possible for the material contained within the vial of "Calcitonin gene-related peptide 1, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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