SDS-PAGE
Calsequestrin-1 / CASQ1 Recombinant Protein | CASQ1 recombinant protein
Recombinant Human Calsequestrin-1 / CASQ1 Protein
Gene Names
CASQ1; CASQ; PDIB1; VMCQA
Purity
> 80% as determined by reducing SDS-PAGE
Synonyms
Calsequestrin-1 / CASQ1; N/A; Recombinant Human Calsequestrin-1 / CASQ1 Protein; CASQ1; CASQ; PDIB1; VMCQA; CASQ1 recombinant protein
Host
E Coli
Purity/Purification
> 80% as determined by reducing SDS-PAGE
Form/Format
Liquid; Lyophilized suppplied as sterile 50mM Tris, 10% glycerol, pH 7.5
Concentration
1.13mg/ml (varies by lot)
Sequence Length
396
Sequence
Gln35-Asp396
Preparation and Storage
Ships on blue ice.
Store it under sterile conditions at -20°C to -80°C upon receiving.
Recommend to aliquot the protein into smaller quantities for optimal storage.
Store it under sterile conditions at -20°C to -80°C upon receiving.
Recommend to aliquot the protein into smaller quantities for optimal storage.
SDS-PAGE
SDS-PAGE
Related Product Information for CASQ1 recombinant protein
Background: Calsequestrin-1 is an isoform of calsequestrin. Calsequestrin is a calcium-binding protein of the sarcoplasmic reticulum. It helps hold calcium in the cisterna of the sarcoplasmic reticulum after a muscle contraction, even though the concentration of calcium in the sarcoplasmic reticulum is much higher than in the cytosol. Two forms of calsequestrin have been identified: Calsequestrin-2 and Calsequestrin-1. Calsequestrin-1 is found in fast skeletal muscle. The release of calsequestrin-bound calcium (through a calcium release channel) triggers muscle contraction. The active protein is not highly structured, more than 50% of it adopting a random coil conformation. When calcium binds there is a structural change whereby the alpha-helical content of the protein increases from 3 to 11%. Both forms of calsequestrin are phosphorylated by casein kinase 2, but the cardiac form is phosphorylated more rapidly and to a higher degree. Calsequestrin-1 is also secreted in the gut where it deprives bacteria of calcium ions.
Description: A DNA sequence encoding the mature form of human CASQ1 (P31415) (Gln35-Asp396) was expressed with a N-terminal Met.
Description: A DNA sequence encoding the mature form of human CASQ1 (P31415) (Gln35-Asp396) was expressed with a N-terminal Met.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
Molecular MasS: 41.8 kDa
AP Molecular Mass: 52 kDa
AP Molecular Mass: 52 kDa
NCBI Official Full Name
calsequestrin-1
NCBI Official Synonym Full Names
calsequestrin 1
NCBI Official Symbol
CASQ1
NCBI Official Synonym Symbols
CASQ; PDIB1; VMCQA
NCBI Protein Information
calsequestrin-1
UniProt Protein Name
Calsequestrin-1
UniProt Gene Name
CASQ1
UniProt Synonym Gene Names
CASQ
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Product Notes
The CASQ1 casq1 (Catalog #AAA173523) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Calsequestrin-1 / CASQ1, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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