Application Data
5-Hydroxytryptamine (Serotonin) Receptor 1F (HTR1F) Cell Line | HTR1F cell line
Human 5-hydroxytryptamine (serotonin) receptor 1F (HTR1F) ACTOne Stable Cell Line
Gene Names
HTR1F; 5HT6; MR77; 5-HT1F; HTR1EL; 5-HT-1F
Synonyms
5-Hydroxytryptamine (Serotonin) Receptor 1F (HTR1F); N/A; Human 5-hydroxytryptamine (serotonin) receptor 1F (HTR1F) ACTOne Stable Cell Line; HTR1F cell line
Sequence Length
366
Detection Range
0.5-32ng/mL
Sensitivity
0.117ng/ml
Dry Ice Shipment
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Preparation and Storage
Dry Ice Shipment: Extra charge fee may add to your shipping cost as dry ice is required to ship this product.
Shipping Note: Product is available for shipment in the United States, Canada and European countries. Please inquire for shipment to other countries.
Shipping Note: Product is available for shipment in the United States, Canada and European countries. Please inquire for shipment to other countries.
Application Data
Application Data
Application Data
Application Data
Related Product Information for HTR1F cell line
Background/Introduction: Hsp90 is a highly conserved and essential stress protein that is expressed in all eukaryotic cells. From a functional perspective, hsp90 participates in the folding, assembly, maturation, and stabilization of specific proteins as an integral component of a chaperone complex (1-4). Despite its label of being a heat-shock protein, hsp90 is one of the most highly expressed proteins in unstressed cells (1-2% of cytosolic protein). It carries out a number of housekeeping functions-including controlling the activity, turnover, and trafficking of a variety of proteins. Most of the hsp90-regulated proteins that have been discovered to date are involved in cell signaling (5-6). The number of proteins now known to interact with Hsp90 is about 100. Target proteins include the kinases v-Src, Wee1, and c-Raf, transcriptional regulators such as p53 and steroid receptors, and the polymerases of the hepatitis B virus and telomerase(3). When bound to ATP, Hsp90 interacts with co-chaperones Cdc37, p23, and an assortment of immunophilin-like proteins, forming a complex that stabilizes and protects target proteins from proteasomal degradation. In most cases, hsp90-interacting proteins have been shown to co-precipitate with hsp90 when carrying out immune-oadsorption studies, and to exist in cytosolic heterocomplexes with it. In a number of cases, variations in hsp90 expression or hsp90 mutation has been shown to degrade signaling function via the protein or to impair a specific function of the protein (such as steroid binding, kinase activity) in vivo. Ansamycin antibiotics, such as geldanamycin and radicicol, inhibit hsp90 function (7).
Product Categories/Family for HTR1F cell line
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
41,709 Da
NCBI Official Full Name
5-hydroxytryptamine receptor 1F
NCBI Official Synonym Full Names
5-hydroxytryptamine receptor 1F
NCBI Official Symbol
HTR1F
NCBI Official Synonym Symbols
5HT6; MR77; 5-HT1F; HTR1EL; 5-HT-1F
NCBI Protein Information
5-hydroxytryptamine receptor 1F
UniProt Protein Name
5-hydroxytryptamine receptor 1F
UniProt Gene Name
HTR1F
UniProt Synonym Gene Names
HTR1EL; 5-HT-1F; 5-HT1F
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Product Notes
The HTR1F htr1f (Catalog #AAA62072) is a Cell Line and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "5-Hydroxytryptamine (Serotonin) Receptor 1F (HTR1F), Cell Line" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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