Dipeptidyl aminopeptidase-like protein 6 Recombinant Protein | DPP6 recombinant protein

Recombinant Rat Dipeptidyl aminopeptidase-like protein 6

Cat. Num. AAA113262

• Gene Names: Dpp6; DPP VI
• Purity: Greater or equal to 85% purity as determined by SDS-PAGE.
• Synonyms: Dipeptidyl aminopeptidase-like protein 6; N/A; Recombinant Rat Dipeptidyl aminopeptidase-like protein 6; DPPX; Dipeptidyl aminopeptidase-related protein; Dipeptidyl peptidase 6; Dipeptidyl peptidase IV-like protein; Dipeptidyl peptidase VI; DPP VI; DPP6 recombinant protein

• Host: E Coli or Yeast or Baculovirus or Mammalian Cell
• Purity/Purification: Greater or equal to 85% purity as determined by SDS-PAGE.
• Form/Format: Lyophilized or liquid (Format to be determined during the manufacturing process)
• Sequence Positions: 111-859aa; Extracellular Domain
• Sequence: LTPAEDTSLSQKKKVTVEDLFSEDFKIHDPEAKWISDKEFIYRERKGSVILRNVETNNSTVLIEGKKIESLRAIRYEISPDKEYALFSYNVEPVYQHSHTGYYVLSKIPHGDPQSLDPPEVSNAKLQYAGWGPKGQQLIFIFENNIYYCAHVGKQAIRVVSTGKEGVIYNGLSDWLYEEEILKSHIAHWWSPDGTRLAYATINDSRVPLMELPTYTGSVYPTVKPYHYPKAGSENPSISLHVIGLNGPTHDLEMMPPDDPRMREYYITMVKWATSTKVAVTWLNRAQNVSILTLCDATTGVCTKKHEDESEAWLHRQNEEPVFSKDGRKFFFVRAIPQGGRGKFYHITVSSSQPNSSNDNIQSITSGDWDVTEILTYDEKRNKLYFLSTEDLPRRRHLYSANTVDDFNRQCLSCDLVENCTYVSASFSHNMDFFLLKCEGPGVPTVTVHNTTDKRRMFDLEANEQVQKAIYDRQMPKIEYRKIEVEDYSLPMQILKPATFTDTAHYPLLLVVDGTPGSQSVSERFEVTWETVLVSSHGAVVVKCDGRGSGFQGTKLLHEVRRRLGFLEEKDQMEAVRTMLKEQYIDKTRVAVFGKDYGGYLSTYILPAKGENQGQTFTCGSALSPITDFKLYASAFSERYLGLHGLDNRAYEMTKLAHRVSALEDQQFLIIHATADEKIHFQHTAELITQLIKGKANYSLQIYPDESHYFHSVALKQHLYRSIIGFFVECFRIQDKLPTATAKEDEEED

• Preparation and Storage: Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.

SDS-PAGE

Related Product Information for DPP6 recombinant protein

Promotes cell surface expression of the potassium channel KCND2. Modulates the activity and gating characteristics of the potassium channel KCND2. Has no dipeptidyl aminopeptidase activity.

References

Differential expression of two distinct forms of mRNA encoding members of a dipeptidyl aminopeptidase family.Wada K., Yokotani N., Hunter C., Doi K., Wenthold R.J., Shimasaki S.Proc. Natl. Acad. Sci. U.S.A. 89:197-201(1992) The CD26-related dipeptidyl aminopeptidase-like protein DPPX is a critical component of neuronal A-type K+ channels.Nadal M.S., Ozaita A., Amarillo Y., Vega-Saenz de Miera E., Ma Y., Mo W., Goldberg E.M., Misumi Y., Ikehara Y., Neubert T.A., Rudy B.Neuron 37:449-461(2003) Multiprotein assembly of Kv4.2, KChIP3 and DPP10 produces ternary channel complexes with ISA-like properties.Jerng H.H., Kunjilwar K., Pfaffinger P.J.J. Physiol. (Lond.) 568:767-788(2005) A novel N-terminal motif of dipeptidyl peptidase-like proteins produces rapid inactivation of KV4.2 channels by a pore-blocking mechanism.Jerng H.H., Dougherty K., Covarrubias M., Pfaffinger P.J.Channels 3:448-461(2009) The dipeptidyl-peptidase-like protein DPP6 determines the unitary conductance of neuronal Kv4.2 channels.Kaulin Y.A., De Santiago-Castillo J.A., Rocha C.A., Nadal M.S., Rudy B., Covarrubias M.J. Neurosci. 29:3242-3251(2009)

NCBI and Uniprot Product Information

• NCBI GI #: 12408298
• NCBI GeneID: 29272
• NCBI Accession #: NP_074041.1
• NCBI GenBank Nucleotide #: NM_022850.1
• UniProt Accession #: P46101
• Molecular Weight: 87.6 kDa
• NCBI Official Full Name: dipeptidyl aminopeptidase-like protein 6
• NCBI Official Synonym Full Names: dipeptidyl peptidase like 6
• NCBI Official Symbol: Dpp6
• NCBI Official Synonym Symbols: DPP VI
• NCBI Protein Information: dipeptidyl aminopeptidase-like protein 6
• UniProt Protein Name: Dipeptidyl aminopeptidase-like protein 6
• UniProt Gene Name: Dpp6
• UniProt Synonym Gene Names: DPP VI
• UniProt Entry Name: DPP6_RAT