Application Data
FGF18 active protein
Recombinant Human FGF18
Gene Names
FGF18; ZFGF5; FGF-18
Purity
>95% as determined by SDS-PAGE
Synonyms
FGF18; N/A; Recombinant Human FGF18; Fibroblast Growth Factor-18; zFGF5; FGF18 active protein
Host
E Coli
Purity/Purification
>95% as determined by SDS-PAGE
Form/Format
Lyophilized from a 0.2 um filtered solution in phosphate buffer, NaCl, KCl and EDTA (pH 7.5)
Sequence Length
207
Bioactivity
The bioactivity was determined in a 3T3 cell proliferation assay. The ED50 was in the range of 0.05-0.1 ng/ml.
Endotoxin Level
<1.0 EU/ug of recombinant protein as determined by the LAL method
Reconstitution
A quick spin of the vial followed by reconstitution in sterile distilled water to a concentration not less than 0.1 mg/mL is recommended. Please note, filter sterilization is a must following reconstitution. This solution can then be diluted into other buffers.
Preparation and Storage
The lyophilized protein is stable for at least one year from date of receipt at-70 degree C. Upon reconstitution, this cytokine can be stored in working aliquots at 2-8 degree C for one month, or at-20 degree C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.
Application Data
Application Data
Application Data
Application Data
Related Product Information for FGF18 active protein
Human FGF18 is a member of the FGF family, a group of related proteins having broad mitogenic and cell survival activity. Members of this family have key roles in prenatal development, as well as postnatal growth and tissue regeneration. FGF18 promotes chondrogenesis, through interaction with FGFR3. It has been demonstrated to cause an increase in cartilage in a murine osteoarthritis model. It has also been implicated in the proliferation of tissues, notably the liver and small intestine. FGF18 also signals through FGFR 1c, 2c and 4. Recombinant Human FGF18 is a 20.4 kDa heparin binding growth factor.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
20.4 kDa
NCBI Official Full Name
fibroblast growth factor 18
NCBI Official Synonym Full Names
fibroblast growth factor 18
NCBI Official Symbol
FGF18
NCBI Official Synonym Symbols
ZFGF5; FGF-18
NCBI Protein Information
fibroblast growth factor 18
UniProt Protein Name
Fibroblast growth factor 18
UniProt Gene Name
FGF18
UniProt Synonym Gene Names
FGF-18
UniProt Entry Name
FGF18_HUMAN
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Product Notes
The FGF18 fgf18 (Catalog #AAA214296) is an Active Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "FGF18, Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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