NP-1 active protein
Human NP-1
Gene Names
NPTX1; NP1
Reactivity
Human
Purity
>98 % by SDS-PAGE, HPLC analysis
Synonyms
NP-1; N/A; Human NP-1; Recombinant Human NP-1; NP-1 active protein
Host
E Coli
Reactivity
Human
Purity/Purification
>98 % by SDS-PAGE, HPLC analysis
Form/Format
Lyophilized
Sequence
ACYCRIPACI AGERRYGYCI YQGRLWAFCC
Sequence Length
432
Endotoxin Level
< 0.1 ng/ug of protein (1EU/ug).
Biological Activity
Determined by its ability to chemoattract immature dendritic cells using a concentration of 1.0-10.0 ng/ml.
Reconstitution
Centrifuge the vial prior to opening. Reconstitute in
water to a concentration of 0.1-1.0 mg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20°C to -80°C.
Preparation and Storage
The lyophilized protein is stable at room temperature for 1 month and at 4°C for 6 months. Reconstituted working aliquots are stable for 1 week at 2°C to 8°C and for 3 months at -20°C to -80°C.
Related Product Information for NP-1 active protein
Defensins (alpha and beta) are cationic peptides with a broad spectrum of antimicrobial activity that comprise an important arm of the innate immune system. The alpha-defensins which include NP-1, NP-2 and NP-3, are distinguished from the beta-defensins by the pairing of their three disulfide bonds. In addition to antimicrobial activity, NP-1 exhibits chemotactic activity on dendritic cells. NP-1 is expressed as the C-terminal portion of an inactive precursor protein, which also contains a 19 amino acid N-terminal signal sequence and a 45 amino acid polypeptide. NP-1 contains a six-cysteine motif that forms three intra-molecular disulfide bonds. Recombinant human NP-1 is a 3.4 kDa protein containing 30 amino acid residues.
Product Categories/Family for NP-1 active protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
3.4 kDa
NCBI Official Full Name
neuronal pentraxin-1
NCBI Official Synonym Full Names
neuronal pentraxin I
NCBI Official Symbol
NPTX1
NCBI Official Synonym Symbols
NP1
NCBI Protein Information
neuronal pentraxin-1; NP-I
UniProt Protein Name
Neuronal pentraxin-1
UniProt Gene Name
NPTX1
UniProt Synonym Gene Names
NP1; NP-I
UniProt Entry Name
NPTX1_HUMAN
Similar Products
Product Notes
The NP-1 nptx1 (Catalog #AAA79176) is an Active Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The Human NP-1 reacts with Human and may cross-react with other species as described in the data sheet. The amino acid sequence is listed below: ACYCRIPACI AGERRYGYCI YQGRLWAFCC. It is sometimes possible for the material contained within the vial of "NP-1, Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.