VE-Statin/EGFL-7 active protein
Human VE-Statin/EGFL7
Gene Names
EGFL7; NEU1; ZNEU1; VE-STATIN; RP11-251M1.2
Reactivity
Human
Purity
> 98% by SDS-PAGE & HPLC analyses
Synonyms
VE-Statin/EGFL-7; N/A; Human VE-Statin/EGFL7; EGFL7; NEU1; ZNEU1; VE-STATIN; RP11-251M1.2; NOTCH4-like protein; VE-Statin/EGFL-7 active protein
Host
E Coli
Reactivity
Human
Purity/Purification
> 98% by SDS-PAGE & HPLC analyses
Form/Format
Lyophilized
Sequence
MYRPGRRVCA VRAHGDPVSE SFVQRVYQPF LTTCDGHRAC STYRTI YRTA YRRSPGLAPA RPRYACCPGW KRTSGLPGAC GAAICQPPCR N GGSCVQPGR CRCPAGWRGD TCQSDVDECS ARRGGCPQRC VNTAGSY WCQ CWEGHSLSAD GTLCVPKGGP PRVAPNPTGV DSAMKEEVQR LQ SRVDLLEE KLQLVLAPLH SLASQALEHG LPDPGSLLVH SFQQLGRI DS LSEQISFLEE QLGSCSCKKD S
Sequence Length
251
Endotoxin Level
<0.1ng/ug of protein (1EU/ug)
Reconstitution
Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/ml. Do not vortex. This solution can be stored at 2-8 degree C for up to 1 week. FOr extended storage, it is recommended to further dilute in a buffer containing a carrier protein( e.g. 0.1% BSA/HSA) and store in aliquots at -20 degree C to -80 degree C.
Biological Activity
Data not available.
Preparation and Storage
The lyophilized protein is stable at room temperature for 1 month and at 4 degree C for 6 months. Reconsituted working aliquots are stable for 1 week at 2 degree C to 8 degree C and for 3 months at -20 degree C to -80 degree C.
Avoid repeated freeze and thaw cycles!
Avoid repeated freeze and thaw cycles!
Related Product Information for VE-Statin/EGFL-7 active protein
EGF-L7 (Epidermal Growth Factor Like Protein 7, Multiple EGF Like Domains Protein 7, VE Statin) is a multi-domain protein containing two EGF like domains and one EMI domain. It is expressed almost exclusively in endothelial cells and functions to promote normal development of the vascular system, particularly tubulogenesis. EGF-L7 is capable of antagonistic binding to Notch receptors resulting in the inhibition of Notch signaling in HUVEC and neural stem cells. In research models inducing hypoxia and subsequent reoxygenation, (H/R), EGF-L7 can inhibit ICAM-1 expression and enhance the inhibition of NF-kappaB activation. Additionally, EGF-L7 can chemoattract endothelial cells and bind to the extracellular matrix. The overexpression of EGF-L7 is observed in various cancers, and is generally correlated with increased metastasis and a poor prognosis. Recombinant human EGF-L7 is a 27.4 kDa protein containing 251 amino acid residues.
Product Categories/Family for VE-Statin/EGFL-7 active protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
27.4kDa
NCBI Official Full Name
epidermal growth factor-like protein 7
NCBI Official Synonym Full Names
EGF-like-domain, multiple 7
NCBI Official Symbol
EGFL7
NCBI Official Synonym Symbols
NEU1; ZNEU1; VE-STATIN; RP11-251M1.2
NCBI Protein Information
epidermal growth factor-like protein 7; EGF-like protein 7; NOTCH4-like protein; vascular endothelial statin; multiple EGF-like domains protein 7; multiple epidermal growth factor-like domains protein 7
UniProt Protein Name
Epidermal growth factor-like protein 7
UniProt Gene Name
EGFL7
UniProt Synonym Gene Names
MEGF7; EGF-like protein 7; Multiple EGF-like domains protein 7; VE-statin
UniProt Entry Name
EGFL7_HUMAN
Similar Products
Product Notes
The VE-Statin/EGFL-7 egfl7 (Catalog #AAA79165) is an Active Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The Human VE-Statin/EGFL7 reacts with Human and may cross-react with other species as described in the data sheet. The amino acid sequence is listed below: MYRPGRRVCA VRAHGDPVSE SFVQRVYQPF LTTCDGHRAC STYRTI YRTA YRRSPGLAPA RPRYACCPGW KRTSGLPGAC GAAICQPPCR N GGSCVQPGR CRCPAGWRGD TCQSDVDECS ARRGGCPQRC VNTAGSY WCQ CWEGHSLSAD GTLCVPKGGP PRVAPNPTGV DSAMKEEVQR LQ SRVDLLEE KLQLVLAPLH SLASQALEHG LPDPGSLLVH SFQQLGRI DS LSEQISFLEE QLGSCSCKKD S. It is sometimes possible for the material contained within the vial of "VE-Statin/EGFL-7, Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.