IFN-gamma active protein
Mouse IFN-gamma
Gene Names
Ifng; Ifg; IFN-g
Reactivity
Mouse
Purity
> 98% by SDS-PAGE & HPLC analyses
Synonyms
IFN-gamma; N/A; Mouse IFN-gamma; Recombinant Murine IFN-gamma , Ifng, Ifg, IFN-g; IFN-gamma active protein
Host
E Coli
Reactivity
Mouse
Purity/Purification
> 98% by SDS-PAGE & HPLC analyses
Form/Format
Lyophilized
Sequence
MHGTVIESLE SLNNYFNSSG IDVEEKSLFL DIWRNWQKDG DMKILQ SQII SFYLRLFEVL KDNQAISNNI SVIESHLITT FFSNSKAKKD A FMSIAKFEV NNPQVQRQAF NELIRVVHQL LPESSLRKRK RSRC
Sequence Length
134
Endotoxin Level
< 0.1 ng/ug of protein (<1EU/ug)
Biological Activity
Determined by its ability to inhibit the proliferation of murine WEHI-279 cells. The expected ED50 is <= 0.2 ng/ml, corresponding to a specific activity of >= 5 x 10^6 units/mg.
Length
134
Reconstitution
Centrifuge vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/m. Do not vortex. This solution can be stored at 2°C to 8°C for up to 1 week. For extended storage it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20°C to -80°C.
Preparation and Storage
The lyophilized protein is stable at room temperature for 1 month and at 4°C for 6 months. Reconstituted working aliquots are stable for 1 week at 2°C to 8°C and for 12 months at -20°C to -80°C.
Related Product Information for IFN-gamma active protein
IFN-gamma is an acid-labile interferon produced by CD4 and CD8 T lymphocytes as well as activated NK cells. IFN-gamma receptors are present in most immune cells, which respond to IFN-gamma signaling by increasing the surface expression of class I MHC proteins. This promotes the presentation of antigen to T-helper (CD4+) cells. IFN-gamma signaling in antigen-presenting cells and antigen-recognizing B and T lymphocytes regulates the antigen-specific phases of the immune response. Additionally, IFN-gamma stimulates a number of lymphoid cell functions including the anti-microbial and anti-tumor responses of macrophages, NK cells, and neutrophils. Human IFN-gamma species-specific and is biologically active only in human and primate cells. Recombinant murine IFN-gamma is a 15.6 kDa protein containing 134 amino acid residues.
Product Categories/Family for IFN-gamma active protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
15.6 kDa
NCBI Official Full Name
interferon gamma
NCBI Official Synonym Full Names
interferon gamma
NCBI Official Symbol
Ifng
NCBI Official Synonym Symbols
Ifg; IFN-g
NCBI Protein Information
interferon gamma; IFN-gamma; gamma interferon
UniProt Protein Name
Interferon gamma
UniProt Gene Name
Ifng
UniProt Synonym Gene Names
IFN-gamma
UniProt Entry Name
IFNG_MOUSE
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Product Notes
The IFN-gamma ifng (Catalog #AAA79149) is an Active Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The Mouse IFN-gamma reacts with Mouse and may cross-react with other species as described in the data sheet. The amino acid sequence is listed below: MHGTVIESLE SLNNYFNSSG IDVEEKSLFL DIWRNWQKDG DMKILQ SQII SFYLRLFEVL KDNQAISNNI SVIESHLITT FFSNSKAKKD A FMSIAKFEV NNPQVQRQAF NELIRVVHQL LPESSLRKRK RSRC. It is sometimes possible for the material contained within the vial of "IFN-gamma, Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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