Transcriptional regulator ERG Recombinant Protein | ERG recombinant protein

Recombinant Human Transcriptional regulator ERG

Cat. Num. AAA18455

• Gene Names: ERG; p55; erg-3
• Purity: Greater or equal to 85% purity as determined by SDS-PAGE.
• Synonyms: Transcriptional regulator ERG; N/A; Recombinant Human Transcriptional regulator ERG; Transforming protein ERG; ERG recombinant protein

• Host: E Coli or Yeast or Baculovirus or Mammalian Cell
• Purity/Purification: Greater or equal to 85% purity as determined by SDS-PAGE.
• Form/Format: Lyophilized or liquid (Format to be determined during the manufacturing process)
• Sequence Positions: 1-486aa; Full Length of Isoform 5
• Sequence: MIQTVPDPAAHIKEALSVVSEDQSLFECAYGTPHLAKTEMTASSSSDYGQTSKMSPRVPQQDWLSQPPARVTIKMECNPSQVNGSRNSPDECSVAKGGKMVGSPDTVGMNYGSYMEEKHMPPPNMTTNERRVIVPADPTLWSTDHVRQWLEWAVKEYGLPDVNILLFQNIDGKELCKMTKDDFQRLTPSYNADILLSHLHYLRETPLPHLTSDDVDKALQNSPRLMHARNTGGAAFIFPNTSVYPEATQRITTRPDLPYEPPRRSAWTGHGHPTPQSKAAQPSPSTVPKTEDQRPQLDPYQILGPTSSRLANPGWTQ
• Sequence Length: 486

• Preparation and Storage: Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.

SDS-PAGE

Related Product Information for ERG recombinant protein

Transcriptional regulator. May participate in transcriptional regulation through the recruitment of SETDB1 histone methyltransferase and subsequent modification of local chromatin structure.

Product Categories/Family for ERG recombinant protein

Transcription

References

erg, a human ets-related gene on chromosome 21 alternative splicing, polyadenylation, and translation.Rao V.N., Papas T.S., Shyam E., Reddy P.Science 237:635-639(1987) The erg gene a human gene related to the ets oncogene.Reddy E.S.P., Rao V.N., Papas T.S.Proc. Natl. Acad. Sci. U.S.A. 84:6131-6135(1987) Detailed mapping of the ERG-ETS2 interval of human chromosome 21 and comparison with the region of conserved synteny on mouse chromosome 16.Owczarek C.M., Portbury K.J., Hardy M.P., O'Leary D.A., Kudoh J., Shibuya K., Shimizu N., Kola I., Hertzog P.J.Gene 324:65-77(2004) Complete sequencing and characterization of 21,243 full-length human cDNAs.Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S., Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.Nat. Genet. 36:40-45(2004) Differentially spliced erg-3 product functions as a transcriptional activator.Prasad D.D., Rao V.N., Lee L., Reddy E.S.Oncogene 9:669-673(1994) ERG gene is translocated in an Ewing's sarcoma cell line.Dunn T., Praissman L., Hagag N., Viola M.V.Cancer Genet. Cytogenet. 76:19-22(1994) An RNA-binding protein gene, TLS/FUS, is fused to ERG in human myeloid leukemia with t(16;21) chromosomal translocation.Ichikawa H., Shimizu K., Hayashi Y., Ohki M.Cancer Res. 54:2865-2868(1994) ELF4 is fused to ERG in a case of acute myeloid leukemia with a t(X;21) (q25-26;q22) .Moore S.D., Offor O., Ferry J.A., Amrein P.C., Morton C.C., Dal Cin P.Leuk. Res. 30:1037-1042(2006) Molecular composition of IMP1 ribonucleoprotein granules.Joeson L., Vikesaa J., Krogh A., Nielsen L.K., Hansen T., Borup R., Johnsen A.H., Christiansen J., Nielsen F.C.Mol. Cell. Proteomics 6:798-811(2007) Diversity in structure and function of the Ets family PNT domains.Mackereth C.D., Scharpf M., Gentile L.N., MacIntosh S.E., Slupsky C.M., McIntosh L.P.J. Mol. Biol. 342:1249-1264(2004)

NCBI and Uniprot Product Information

• NCBI GI #: 209954797
• NCBI GeneID: 2078
• NCBI Accession #: NP_001129626.1
• NCBI GenBank Nucleotide #: NM_001136154.1
• UniProt Accession #: P11308; Q16113; Q6XXX4; Q6XXX5; Q8IXK9; B4DTW5; B4E0T4
• Molecular Weight: 56.6 kDa
• NCBI Official Full Name: transcriptional regulator ERG isoform 3
• NCBI Official Synonym Full Names: v-ets avian erythroblastosis virus E26 oncogene homolog
• NCBI Official Symbol: ERG
• NCBI Official Synonym Symbols: p55; erg-3
• NCBI Protein Information: transcriptional regulator ERG
• UniProt Protein Name: Transcriptional regulator ERG
• UniProt Gene Name: ERG
• UniProt Entry Name: ERG_HUMAN