GTPase Activating Protein Recombinant Protein | G3BP1 recombinant protein

Recombinant Human GTPase Activating Protein (SH3 domain) Binding Protein 1

Cat. Num. AAA38862

• Gene Names: G3BP1; G3BP; HDH-VIII
• Purity: Greater than 85.0% as determined by SDS-PAGE.
• Synonyms: GTPase Activating Protein; N/A; Recombinant Human GTPase Activating Protein (SH3 domain) Binding Protein 1; G3BP1 Human; GTPase Activating Protein (SH3 domain) Binding Protein 1 Human Recombinant; Ras GTPase-activating protein-binding protein 1; G3BP-1; ATP-dependent DNA helicase VIII; hDH VIII; GAP SH3 domain-binding protein 1; G3BP1; G3BP; HDH-VIII; MGC111040; G3BP1 recombinant protein

• Host: E Coli
• Purity/Purification: Greater than 85.0% as determined by SDS-PAGE.
• Form/Format: The G3BP1 solution (0.5 mg/ml) contains 20mM Tris-HCl buffer (pH8.0), 10% glycerol, 2mM DTT and 100mM NaCl.; Sterile Filtered colorless solution.
• Sequence: MVMEKPSPLL VGREFVRQYY TLLNQAPDML HRFYGKNSSY VHGGLDSNGK PADAVYGQKE IHRKVMSQNF TNCHTKIRHV DAHATLNDGV VVQVMGLLSN NNQALRRFMQ TFVLAPEGSV ANKFYVHNDI FRYQDEVFGG FVTEPQEESE EEVEEPEERQ QTPEVVPDDS GTFYDQAVVS NDMEEHLEEP VAEPEPDPEP EPEQEPVSEI QEEKPEPVLE ETAPEDAQKS SSPAPADIAQ TVQEDLRTFS WASVTSKNLP PSGAVPVTGI PPHVVKVPAS QPRPESKPES QIPPQRPQRD QRVREQRINI PPQRGPRPIR EAGEQGDIEP RRMVRHPDSH QLFIGNLPHE VDKSELKDFF QSYGNVVELR INSGGKLPNF GFVVFDDSEP VQKVLSNRPI MFRGEVRLNV EEKKTRAARE GDRRDNRLRG PGGPRGGLGG GMRGPPRGGM VQKPGFGVGR GLAPRQVEHHHHHH
• Sequence Length: 466

• Preparation and Storage: Store at 4 degree C if entire vial will be used within 2-4 weeks. Store, frozen at -20 degree C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.

Related Product Information for G3BP1 recombinant protein

Description: G3BP1 Human Recombinant fused with an 8 amino acid His tag at C-terminus produced in E Coli is a single, non-glycosylated, polypeptide chain containing 474 amino acids (1-466 a.a.) and having a molecular mass of 53.2kDa.The G3BP1 is purified by proprietary chromatographic techniques.

Introduction: G3BP1 belongs to the heterogeneous nuclear RNA-binding proteins and is also an element of the Ras signal transduction pathway. G3BP1 is one of the DNA-unwinding enzymes that favors partially unwound 3'-tailed substrates and is also able to unwind partial RNA/DNA and RNA/RNA duplexes in an ATP-dependent fashion. G3BP1 binds specifically to the Ras-GTPase-activating protein by associating with its SH3 domain. In addition, G3BP1 cleaves exclusively between cytosine and adenine and cleaves MYC mRNA preferentially at the 3'-UTR.

Product Categories/Family for G3BP1 recombinant protein

Enzymes

NCBI and Uniprot Product Information

• NCBI GI #: 5031703
• NCBI GeneID: 10146
• NCBI Accession #: NP_005745.1
• NCBI GenBank Nucleotide #: NM_005754.2
• UniProt Accession #: Q13283; Q5HYE9
• Molecular Weight: 13,874 Da
• NCBI Official Full Name: ras GTPase-activating protein-binding protein 1
• NCBI Official Synonym Full Names: GTPase activating protein (SH3 domain) binding protein 1
• NCBI Official Symbol: G3BP1
• NCBI Official Synonym Symbols: G3BP; HDH-VIII
• NCBI Protein Information: ras GTPase-activating protein-binding protein 1; ATP-dependent DNA helicase VIII; G3BP-1; GAP SH3 domain-binding protein 1; GAP binding protein; Ras-GTPase-activating protein SH3-domain-binding protein; RasGAP-associated endoribonuclease G3BP
• UniProt Protein Name: Ras GTPase-activating protein-binding protein 1
• UniProt Gene Name: G3BP1
• UniProt Synonym Gene Names: G3BP; G3BP-1; hDH VIII
• UniProt Entry Name: G3BP1_HUMAN