SDS-PAGE
Giardia intestinalis Endoribonuclease Dicer-like Recombinant Protein | GL50803_103887 recombinant protein
Recombinant Giardia intestinalis Endoribonuclease Dicer-like
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Giardia intestinalis Endoribonuclease Dicer-like; N/A; Recombinant Giardia intestinalis Endoribonuclease Dicer-like; GL50803_103887 recombinant protein
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
1-754aa; Full Length
Sequence
MHALGHCCTVVTTRGPSHWLLLLDTHLGTLPGFKVSAGRGLPAAEVYFEAGPRVSLSRTDATIVAVYQSILFQLLGPTFPASWTEIGATMPHNEYTFPRFISNPPQFATLAFLPLLSPTSPLDLRALMVTAQLMCDAKRLSDEYTDYSTLSASLHGRMVATPEISWSLYVVLGIDSTQTSLSYFTRANESITYMRYYATAHNIHLRAADLPLVAAVRLDDLKDHQIPAPGSWDDLAPKLRFLPPELCLLLPDEFDLIRVQALQFLPEIAKHICDIQNTICALDKSFPDCGRIGGERYFAITAGLRLDQGRGRGLAGWRTPFGPFGVSHTDVFQRLELLGDAVLGFIVTARLLCLFPDASVGTLVELKMELVRNEALNYLVQTLGLPQLAEFSNNLVAKSKTWADMYEEIVGSIFTGPNGIYGCEEFLAKTLMSPEHSKTVGSACPDAVTKASKRVCMGEAGAHEFRSLVDYACEQGISVFCSSRVSTMFLERLRDIPAEDMLDWYRLGIQFSHRSGLSGPGGVVSVIDIMTHLARGLWLGSPGFYVEQQTDKNESACPPTIPVLYIYHRSVQCPVLYGSLTETPTGPVASKVLALYEKILAYESSGGSKHIAAQTVSRSLAVPIPSGTIPFLIRLLQIALTPHVYQKLELLGDAFLKCSLALHLHALHPTLTEGALTRMRQSAETNSVLGRLTKRFPSVVSEVIIESHPKIQPDSKVYGDTFEAILAAILLACGEEAAGAFVREHVLPQVVADA
Preparation and Storage
Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.
SDS-PAGE
SDS-PAGE
Related Product Information for GL50803_103887 recombinant protein
Involved in cleaving double-stranded RNA in the RNA interference (RNAi) pathway. It produces 21 to 23 bp dsRNAs (siRNAs) which target the selective destruction of homologous RNAs.
References
Genomic minimalism in the early diverging intestinal parasite Giardia lamblia.Morrison H.G., McArthur A.G., Gillin F.D., Aley S.B., Adam R.D., Olsen G.J., Best A.A., Cande W.Z., Chen F., Cipriano M.J., Davids B.J., Dawson S.C., Elmendorf H.G., Hehl A.B., Holder M.E., Huse S.M., Kim U.U., Lasek-Nesselquist E., Manning G., Nigam A., Nixon J.E.J., Palm D., Passamaneck N.E., Prabhu A., Reich C.I., Reiner D.S., Samuelson J., Svard S.G., Sogin M.L.Science 317:1921-1926(2007) Structural basis for double-stranded RNA processing by Dicer.Macrae I.J., Zhou K., Li F., Repic A., Brooks A.N., Cande W.Z., Adams P.D., Doudna J.A.Science 311:195-198(2006) An unusual case of pseudo-merohedral twinning in orthorhombic crystals of Dicer.MacRae I.J., Doudna J.A.Acta Crystallogr. D 63:993-999(2007)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
98.5 kDa
NCBI Official Full Name
Dicer
NCBI Official Symbol
GL50803_103887
NCBI Protein Information
Dicer
UniProt Protein Name
Endoribonuclease Dicer-like
UniProt Gene Name
GL50803_103887
UniProt Entry Name
DCL_GIAIC
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Product Notes
The GL50803_103887 gl50803_103887 (Catalog #AAA115618) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-754aa; Full Length. The amino acid sequence is listed below: MHALGHCCTV VTTRGPSHWL LLLDTHLGTL PGFKVSAGRG LPAAEVYFEA GPRVSLSRTD ATIVAVYQSI LFQLLGPTFP ASWTEIGATM PHNEYTFPRF ISNPPQFATL AFLPLLSPTS PLDLRALMVT AQLMCDAKRL SDEYTDYSTL SASLHGRMVA TPEISWSLYV VLGIDSTQTS LSYFTRANES ITYMRYYATA HNIHLRAADL PLVAAVRLDD LKDHQIPAPG SWDDLAPKLR FLPPELCLLL PDEFDLIRVQ ALQFLPEIAK HICDIQNTIC ALDKSFPDCG RIGGERYFAI TAGLRLDQGR GRGLAGWRTP FGPFGVSHTD VFQRLELLGD AVLGFIVTAR LLCLFPDASV GTLVELKMEL VRNEALNYLV QTLGLPQLAE FSNNLVAKSK TWADMYEEIV GSIFTGPNGI YGCEEFLAKT LMSPEHSKTV GSACPDAVTK ASKRVCMGEA GAHEFRSLVD YACEQGISVF CSSRVSTMFL ERLRDIPAED MLDWYRLGIQ FSHRSGLSGP GGVVSVIDIM THLARGLWLG SPGFYVEQQT DKNESACPPT IPVLYIYHRS VQCPVLYGSL TETPTGPVAS KVLALYEKIL AYESSGGSKH IAAQTVSRSL AVPIPSGTIP FLIRLLQIAL TPHVYQKLEL LGDAFLKCSL ALHLHALHPT LTEGALTRMR QSAETNSVLG RLTKRFPSVV SEVIIESHPK IQPDSKVYGD TFEAILAAIL LACGEEAAGA FVREHVLPQV VADA. It is sometimes possible for the material contained within the vial of "Giardia intestinalis Endoribonuclease Dicer-like, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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