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IHC (Immunohistochemistry)
((3.75ug/ml) staining of paraffin embedded Human Cortex. Steamed antigen retrieval with citrate buffer Ph 6, AP-staining.)
Goat TRPM2 Antibody | anti-TRPM2 antibody
Goat Anti-TRPM2 Antibody
Gene Names
TRPM2; KNP3; EREG1; TRPC7; LTRPC2; NUDT9H; LTrpC-2; NUDT9L1
Reactivity
HumanExpected from sequence similarity: Human, Mouse, Cow
Applications
Immunohistochemistry, Flow Cytometry, Functional Assay, Immunofluorescence, ELISA
Purity
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Synonyms
TRPM2; N/A; Goat Anti-TRPM2 Antibody; transient receptor potential cation channel, subfamily M, member 2; EREG1; KNP3; LTRPC2; MGC133383; NUDT9H; NUDT9L1; TRPC7; estrogen responsive element associated gene 1; long transient receptor potential channel 2; transient receptor potential channel 7; anti-TRPM2 antibody
Host
Goat
Reactivity
Human
Expected from sequence similarity: Human, Mouse, Cow
Expected from sequence similarity: Human, Mouse, Cow
Purity/Purification
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Form/Format
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Sequence Length
1503
Applicable Applications for anti-TRPM2 antibody
IHC (Immunohistochemistry), FCM/FACS (Flow Cytometry), IF (Immunofluorescence), ELISA (Peptide ELISA)
Immunogen
Peptide with sequence C-QQKQRPEQKIED, from the internal region of the protein sequence according to NP_003298.1; NP_001307279.1; NP_001307280.1.
Peptide Sequence
QQKQRPEQKIED
Epitope
Internal region
Preparation and Storage
Aliquot and store at -20 degree C. Minimize freezing and thawing.
IHC (Immunohistochemistry)
((3.75ug/ml) staining of paraffin embedded Human Cortex. Steamed antigen retrieval with citrate buffer Ph 6, AP-staining.)
IHC (Immunohistochemistry)
((3.75ug/ml) staining of paraffin embedded Human Cortex. Steamed antigen retrieval with citrate buffer Ph 6, AP-staining.)
IHC (Immunohistochemisry)
((3.75ug/ml) staining of paraffin embedded Human Pancreas. Steamed antigen retrieval with citrate buffer Ph 6, AP-staining.)
IHC (Immunohistochemisry)
((3.75ug/ml) staining of paraffin embedded Human Pancreas. Steamed antigen retrieval with citrate buffer Ph 6, AP-staining.)
FCM/FACS (Flow Cytometry)
(Flow cytometric analysis of paraformaldehyde fixed Jurkat cells (blue line), permeabilized with 0.5% Triton. Primary incubation 1hr (10ug/ml) followed by Alexa Fluor 488 secondary antibody (1ug/ml). IgG control: Unimmunized goat IgG (black line) f)
FCM/FACS (Flow Cytometry)
(Flow cytometric analysis of paraformaldehyde fixed Jurkat cells (blue line), permeabilized with 0.5% Triton. Primary incubation 1hr (10ug/ml) followed by Alexa Fluor 488 secondary antibody (1ug/ml). IgG control: Unimmunized goat IgG (black line) f)
IF (Immunofluorescence)
(Immunofluorescence analysis of paraformaldehyde fixed A431 cells, permeabilized with 0.15% Triton. Primary incubation 1hr (10ug/ml) followed by Alexa Fluor 488 secondary antibody (2ug/ml), showing nuclear membrane and cytoplasmic staining. The nu)
IF (Immunofluorescence)
(Immunofluorescence analysis of paraformaldehyde fixed A431 cells, permeabilized with 0.15% Triton. Primary incubation 1hr (10ug/ml) followed by Alexa Fluor 488 secondary antibody (2ug/ml), showing nuclear membrane and cytoplasmic staining. The nu)
References
Hecquet CM, Ahmmed GU, Vogel SM, Malik AB: Role of TRPM2 channel in mediating H2O2-induced Ca2+ entry and endothelial hyperpermeability. Circ Res. 2008 Feb 15;102(3):347-55. Epub 2007 Nov 29. PMID: 18048770
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
transient receptor potential cation channel subfamily M member 2 isoform 1
NCBI Official Synonym Full Names
transient receptor potential cation channel subfamily M member 2
NCBI Official Symbol
TRPM2
NCBI Official Synonym Symbols
KNP3; EREG1; TRPC7; LTRPC2; NUDT9H; LTrpC-2; NUDT9L1
NCBI Protein Information
transient receptor potential cation channel subfamily M member 2
UniProt Protein Name
Transient receptor potential cation channel subfamily M member 2
UniProt Gene Name
TRPM2
UniProt Synonym Gene Names
EREG1; KNP3; LTRPC2; TRPC7; LTrpC-2; LTrpC2; TrpC7
UniProt Entry Name
TRPM2_HUMAN
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Product Notes
The TRPM2 trpm2 (Catalog #AAA61830) is an Antibody produced from Goat and is intended for research purposes only. The product is available for immediate purchase. The Goat Anti-TRPM2 Antibody reacts with Human Expected from sequence similarity: Human, Mouse, Cow and may cross-react with other species as described in the data sheet. AAA Biotech's TRPM2 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), FCM/FACS (Flow Cytometry), IF (Immunofluorescence), ELISA (Peptide ELISA). Researchers should empirically determine the suitability of the TRPM2 trpm2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TRPM2, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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