ELISA
(Immobilized recombinant Human LDLR/LDL Receptor at 4?g/mL (100 ?L/well) can bind Human SCARB2 with a linear range of 1.6-379 ng/mL)
LIMPII/SR-B2 Active Protein | SCARB2 active protein
Recombinant Human LIMPII/SR-B2 Protein
Gene Names
SCARB2; AMRF; EPM4; LGP85; CD36L2; HLGP85; LIMP-2; LIMPII; SR-BII
Purity
>97% by SDS-PAGE.
Synonyms
LIMPII/SR-B2; N/A; Recombinant Human LIMPII/SR-B2 Protein; AMRF; CD36L2; EPM4; HLGP85; LGP85; LIMP-2; LIMPII; SR-BII; SCARB2 active protein
Host
HEK293 Cells
Purity/Purification
>97% by SDS-PAGE.
Form/Format
Lyophilized from a 0.22 um filtered solution of PBS, pH 7.4.
Sequence Length
478
Species
Human
Endotoxin
< 0.1 EU/ug of the protein by LAL method.
Biological Activity
Measured by its binding ability in a functional ELISA. Immobilized human LDL at 5 ug/mL (100 uL/well) can bind Recombinant Human SCARB2 Fc Chimera with a linear range of 1.6-379 ng/mL.
Reconstitution
Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water.
Tag
C-hFc, His
Preparation and Storage
Store the lyophilized protein at -20 degree C to -80 degree C for long term.
After reconstitution, the protein solution is stable at -20 degree C for 3 months, at 2-8 degree C for up to 1 week.
After reconstitution, the protein solution is stable at -20 degree C for 3 months, at 2-8 degree C for up to 1 week.
ELISA
(Immobilized recombinant Human LDLR/LDL Receptor at 4?g/mL (100 ?L/well) can bind Human SCARB2 with a linear range of 1.6-379 ng/mL)
ELISA
(Immobilized recombinant Human LDLR/LDL Receptor at 4?g/mL (100 ?L/well) can bind Human SCARB2 with a linear range of 1.6-379 ng/mL)
SDS-PAGE
(Recombinant Human LIMPII/SR-B2 Protein was determined by SDS-PAGE with Coomassie Blue, showing a band at 90-110 kDa.)
SDS-PAGE
(Recombinant Human LIMPII/SR-B2 Protein was determined by SDS-PAGE with Coomassie Blue, showing a band at 90-110 kDa.)
Related Product Information for SCARB2 active protein
Description: Recombinant Human LIMPII/SR-B2 Protein is produced by HEK293 expression system. The target protein is expressed with sequence (Arg27-Thr432) of human LIMPII/SR-B2 (Accession #NP_005497.1) fused with an Fc, 6xHis tag at the C-terminus.
Background: The protein encoded by this gene is a type III glycoprotein that is located primarily in limiting membranes of lysosomes and endosomes. Earlier studies in mice and rat suggested that this protein may participate in membrane transportation and the reorganization of endosomal/lysosomal compartment. The protein deficiency in mice was reported to impair cell membrane transport processes and cause pelvic junction obstruction, deafness, and peripheral neuropathy. Further studies in human showed that this protein is a ubiquitously expressed protein and that it is involved in the pathogenesis of HFMD (hand, foot, and mouth disease) caused by enterovirus-71 and possibly by coxsackievirus A16. Mutations in this gene caused an autosomal recessive progressive myoclonic epilepsy-4 (EPM4), also known as action myoclonus-renal failure syndrome (AMRF). Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Background: The protein encoded by this gene is a type III glycoprotein that is located primarily in limiting membranes of lysosomes and endosomes. Earlier studies in mice and rat suggested that this protein may participate in membrane transportation and the reorganization of endosomal/lysosomal compartment. The protein deficiency in mice was reported to impair cell membrane transport processes and cause pelvic junction obstruction, deafness, and peripheral neuropathy. Further studies in human showed that this protein is a ubiquitously expressed protein and that it is involved in the pathogenesis of HFMD (hand, foot, and mouth disease) caused by enterovirus-71 and possibly by coxsackievirus A16. Mutations in this gene caused an autosomal recessive progressive myoclonic epilepsy-4 (EPM4), also known as action myoclonus-renal failure syndrome (AMRF). Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Product Categories/Family for SCARB2 active protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
UniProt Accession #
NCBI Official Full Name
Lysosome membrane protein 2
NCBI Official Synonym Full Names
scavenger receptor class B member 2
NCBI Official Symbol
SCARB2
NCBI Official Synonym Symbols
AMRF; EPM4; LGP85; CD36L2; HLGP85; LIMP-2; LIMPII; SR-BII
NCBI Protein Information
lysosome membrane protein 2
UniProt Protein Name
Lysosome membrane protein 2
UniProt Gene Name
SCARB2
UniProt Synonym Gene Names
CD36L2; LIMP2; LIMPII; LGP85; LIMP II
UniProt Entry Name
SCRB2_HUMAN
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Product Notes
The SCARB2 scarb2 (Catalog #AAA281423) is an Active Protein produced from HEK293 Cells and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "LIMPII/SR-B2, Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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