SDS-PAGE
(Figure 2. Biotinylated Human CLDN18.2-Nanodisc, DYKDDDDK Tag on SDS-PAGE)
CLDN18.2 protein
Biotinylated Human CLDN18.2 full length protein-synthetic nanodisc
Gene Names
CLDN18; SFTA5; SFTPJ; DKFZp564B2062
Synonyms
CLDN18.2; N/A; Biotinylated Human CLDN18.2 full length protein-synthetic nanodisc; Claudin 18.2; CLDN18.2 protein
Host
HEK293
Form/Format
Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5%-8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions.
Tag
C-DYKDDDDK&Avi
Conjugation
Biotinylated
Preparation and Storage
Store at -20 degree C to -80 degree C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80 degree C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
SDS-PAGE
(Figure 2. Biotinylated Human CLDN18.2-Nanodisc, DYKDDDDK Tag on SDS-PAGE)
SDS-PAGE
(Figure 2. Biotinylated Human CLDN18.2-Nanodisc, DYKDDDDK Tag on SDS-PAGE)
ELISA
(Figure 1. ELISA plate pre-coated by 2 ug/mL (100 uL/well) Anti-CLDN18.2 antibody(DM179); Rabbit mAb can bind Biotinylated Human CLDN18.2 full length protein-synthetic nanodisc (AAA129472) in a linear range of 40–5000 ng/mL. In order to specifically detect AAA129472, HRP Conjugated Streptavidin was used as detection antibody.)
ELISA
(Figure 1. ELISA plate pre-coated by 2 ug/mL (100 uL/well) Anti-CLDN18.2 antibody(DM179); Rabbit mAb can bind Biotinylated Human CLDN18.2 full length protein-synthetic nanodisc (AAA129472) in a linear range of 40–5000 ng/mL. In order to specifically detect AAA129472, HRP Conjugated Streptavidin was used as detection antibody.)
Related Product Information for CLDN18.2 protein
This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. This gene is upregulated in patients with ulcerative colitis and highly overexpressed in infiltrating ductal adenocarcinomas. PKC/MAPK/AP-1 (protein kinase C/mitogen-activated protein kinase/activator protein-1) dependent pathway regulates the expression of this gene in gastric cells. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jun 2010]
Product Categories/Family for CLDN18.2 protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
27,856 Da
NCBI Official Full Name
claudin-18 isoform 2
NCBI Official Synonym Full Names
claudin 18
NCBI Official Symbol
CLDN18
NCBI Official Synonym Symbols
SFTA5; SFTPJ; DKFZp564B2062
NCBI Protein Information
claudin-18; OTTHUMP00000216399; OTTHUMP00000216400; surfactant associated 5; surfactant associated protein J; surfactant, pulmonary associated protein J
UniProt Protein Name
Claudin-18
UniProt Gene Name
CLDN18
UniProt Entry Name
CLD18_HUMAN
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Product Notes
The CLDN18.2 cldn18 (Catalog #AAA129472) is a Protein produced from HEK293 and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "CLDN18.2, Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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