Standard Curve (Sample)
(Mouse Hemojuvelin PicoKine ELISA Kit standard curve)
Hemojuvelin ELISA Kit | HFE2 elisa kit
Mouse Hemojuvelin PicoKine ELISA Kit
Gene Names
Hfe2; HJV; DL-M; Rgmc; AI414844; AI789733; hemojuvelin; 2310035L15Rik; 5230400G09Rik
Reactivity
Mouse. There is no detectable cross-reactivity with other relevant proteins.
Synonyms
Hemojuvelin; N/A; Mouse Hemojuvelin PicoKine ELISA Kit; 2310035L15Rik; 5230400G09Rik; AI414844; AI789733; DL M; Haemojuvelin; HEMOCHROMATOSIS; HEMOCHROMATOSIS DUE TO DEFECT IN HEMOJUVELIN; HEMOCHROMATOSIS DUE TO DEFECT IN HEPCIDIN ANTIMICROBIAL PEPTIDE; HEMOCHROMATOSIS JUVENILE; Hemochromatosis type 2 (juvenile); Hemochromatosis type 2; Hemochromatosis type 2 protein; Hemochromatosis type 2 protein homolog; HEMOCHROMATOSIS, TYPE 2A; HEMOCHROMATOSIS, TYPE 2B; HFE 2; Hfe2; HFE2A; HJV; JH; Juvenile; MGC23953; OTTHUMP00000059680; Repulsive guidance molecule c; RGM C; RGM domain family member C; RGMC ; hemochromatosis type 2 (juvenile); HFE2 elisa kit
Reactivity
Mouse. There is no detectable cross-reactivity with other relevant proteins.
Sequence Length
420
Samples
Cell culture supernates, serum and plasma (heparin, EDTA)
Assay Type
Sandwich
Sensitivity
<10pg/ml
Immunogen
NSO, Q33-D393
Intra-Assay Precision
Sample 1: n=16; Mean(ng/ml): 1.43; Standard deviation: 0.073; CV(%): 5.1 Sample 2: n=16; Mean(ng/ml): 3.06; Standard deviation: 0.113; CV(%): 3.7 Sample 3: n=16; Mean(ng/ml): 5.72; Standard deviation: 0.223; CV(%): 3.9
Inter-Assay Precision
Sample 1: n=24; Mean(ng/ml): 1.46; Standard deviation: 0.11; CV(%): 7.5 Sample 2: n=24; Mean(ng/ml): 3.24; Standard deviation: 0.237; CV(%): 7.3 Sample 3: n=24; Mean(ng/ml): 5.91; Standard deviation: 0.402; CV(%): 6.8
Assay Range
156pg/ml-10,000pg/ml
Preparation and Storage
Store at 4 degree C for 6 months, at -20 degree C for 12 months. Avoid multiple freeze-thaw cycles (Shipped with wet ice.)
Standard Curve (Sample)
(Mouse Hemojuvelin PicoKine ELISA Kit standard curve)
Standard Curve (Sample)
(Mouse Hemojuvelin PicoKine ELISA Kit standard curve)
Related Product Information for HFE2 elisa kit
Description: Sandwich ELISA kit of Quantitative Detection for Mouse Hemojuvelin
Background: Hemojuvelin (HJV/RGMc/HFE2) is a membrane-bound and soluble protein in mammals. It is a member of a three gene family (in vertebrates) called the repulsive guidance molecules. In mouse, the Hemojuvelin protein is encoded by the HFE2 gene, and it is mapped to Chromosome 3. It was concluded that downregulation of hepatic Hemojuvelin during inflammation may induce a temporary elimination of iron sensing. Hemojuvelin is a coreceptor for bone morphogenetic proteins (BMPs), and inhibition of endogenous BMP signaling reduces hepcidin expression and increases serum iron in mice. Furthermore, Hemojuvelin may play inhibitory roles in prostate cancer by suppressing cell growth, adhesion, migration and invasion.
Background: Hemojuvelin (HJV/RGMc/HFE2) is a membrane-bound and soluble protein in mammals. It is a member of a three gene family (in vertebrates) called the repulsive guidance molecules. In mouse, the Hemojuvelin protein is encoded by the HFE2 gene, and it is mapped to Chromosome 3. It was concluded that downregulation of hepatic Hemojuvelin during inflammation may induce a temporary elimination of iron sensing. Hemojuvelin is a coreceptor for bone morphogenetic proteins (BMPs), and inhibition of endogenous BMP signaling reduces hepcidin expression and increases serum iron in mice. Furthermore, Hemojuvelin may play inhibitory roles in prostate cancer by suppressing cell growth, adhesion, migration and invasion.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
21,648 Da
NCBI Official Full Name
hemojuvelin
NCBI Official Synonym Full Names
hemochromatosis type 2 (juvenile) (human homolog)
NCBI Official Symbol
Hfe2
NCBI Official Synonym Symbols
HJV; DL-M; Rgmc; AI414844; AI789733; hemojuvelin; 2310035L15Rik; 5230400G09Rik
NCBI Protein Information
hemojuvelin; RGM domain family member C; repulsive guidance molecule C; hemochromatosis type 2 protein homolog
UniProt Protein Name
Hemojuvelin
UniProt Gene Name
Hfe2
UniProt Synonym Gene Names
Rgmc
UniProt Entry Name
RGMC_MOUSE
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Product Notes
The Mouse. There is no detectable cross-reactivity with other relevant proteins. HFE2 hfe2 (Catalog #AAA46107) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA46107 ELISA Kit recognizes Mouse. There is no detectable cross-reactivity with other relevant proteins. HFE2. It is sometimes possible for the material contained within the vial of "Hemojuvelin, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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