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product-image-AAA129435_ELISA11.jpg ELISA (Figure 3. ELISA plate pre-coated by 2 ug/mL (100 uL/well) Human ACVR2B Protein, hFc Tag can bind Anti-ACVR2B(bimagrumab biosimilar) mAb (AAA129435) in a linear range of 0.64–80 ng/mL.In order to specifically detect AAA129435, mouse anti-human Fab-specific antibody was used as detection antibody.)

Homo sapiens anti-Human ACVR2B Antibody | anti-ACVR2B antibody

Anti-ACVR2B (bimagrumab biosimilar) mAb

Gene Names
ACVR2B; HTX4; ACTRIIB; ActR-IIB
Reactivity
Human
Applications
Flow Cytometry, Functional Assay, ELISA
Synonyms
ACVR2B; N/A; Anti-ACVR2B (bimagrumab biosimilar) mAb; AVR2B; ACTR-IIB; BYM338; anti-ACVR2B antibody
Ordering
Host
Homo sapiens
Reactivity
Human
Isotype
IgG1 (K97R,L117A,L118A)
Form/Format
Lyophilized from sterile PBS, pH 7.4. Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
Applicable Applications for anti-ACVR2B antibody
FCM/FACS (Flow Cytometry), ELISA
Preparation and Storage
Store at -20 degree C to -80 degree C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80 degree C (Avoid repeated freezing and thawing). Lyophilized antibodies are shipped at ambient temperature.

ELISA

(Figure 3. ELISA plate pre-coated by 2 ug/mL (100 uL/well) Human ACVR2B Protein, hFc Tag can bind Anti-ACVR2B(bimagrumab biosimilar) mAb (AAA129435) in a linear range of 0.64–80 ng/mL.In order to specifically detect AAA129435, mouse anti-human Fab-specific antibody was used as detection antibody.)

product-image-AAA129435_ELISA11.jpg ELISA (Figure 3. ELISA plate pre-coated by 2 ug/mL (100 uL/well) Human ACVR2B Protein, hFc Tag can bind Anti-ACVR2B(bimagrumab biosimilar) mAb (AAA129435) in a linear range of 0.64–80 ng/mL.In order to specifically detect AAA129435, mouse anti-human Fab-specific antibody was used as detection antibody.)

FCM/FACS (Flow Cytometry)

(Figure 2. Flow cytometry analysis with 1ug/mL Anti-ACVR2B(bimagrumab biosimilar) mAb (AAA129435) on Expi293 cells transfected with Human ACVR2A protein (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram).)

product-image-AAA129435_FCM13.jpg FCM/FACS (Flow Cytometry) (Figure 2. Flow cytometry analysis with 1ug/mL Anti-ACVR2B(bimagrumab biosimilar) mAb (AAA129435) on Expi293 cells transfected with Human ACVR2A protein (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram).)

FCM/FACS (Flow Cytometry)

(Figure 1. Flow cytometry analysis with 15ug/mL Anti-ACVR2B(bimagrumab biosimilar) mAb (AAA129435) on Expi293 cells transfected with Human ACVR2B protein (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram).)

product-image-AAA129435_FCM15.jpg FCM/FACS (Flow Cytometry) (Figure 1. Flow cytometry analysis with 15ug/mL Anti-ACVR2B(bimagrumab biosimilar) mAb (AAA129435) on Expi293 cells transfected with Human ACVR2B protein (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram).)
Product Categories/Family for anti-ACVR2B antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
93
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
– Da
NCBI Official Full Name
activin receptor type-2B
NCBI Official Synonym Full Names
activin A receptor type 2B
NCBI Official Symbol
ACVR2B
NCBI Official Synonym Symbols
HTX4; ACTRIIB; ActR-IIB
NCBI Protein Information
activin receptor type-2B
UniProt Protein Name
Activin receptor type-2B
UniProt Gene Name
ACVR2B
UniProt Synonym Gene Names
ACTR-IIB
UniProt Entry Name
AVR2B_HUMAN

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Product Notes

The ACVR2B acvr2b (Catalog #AAA129435) is an Antibody produced from Homo sapiens and is intended for research purposes only. The product is available for immediate purchase. The Anti-ACVR2B (bimagrumab biosimilar) mAb reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's ACVR2B can be used in a range of immunoassay formats including, but not limited to, FCM/FACS (Flow Cytometry), ELISA. Researchers should empirically determine the suitability of the ACVR2B acvr2b for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ACVR2B, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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