SDS-PAGE
Haptoglobin protein Recombinant Protein | HP recombinant protein
Recombinant Rat Haptoglobin protein
Gene Names
Hp; Ba1-647
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Haptoglobin protein; N/A; Recombinant Rat Haptoglobin protein; Liver regeneration-related protein LRRG173; Zonulin; HP recombinant protein
Host
E Coli
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Liquid containing glycerol
Sequence Positions
19-346aa; Partial
Sequence
VELGNDATDIEDDSCPKPPEIANGYVEHLVRYRCRQFYKLQTEGDGIYTLNSEKQWVNPAAGDKLPKCEAVCGKPKHPVDQVQRIIGGSMDAKGSFPWQAKMISRHGLTTGATLISDQWLLTTAQNLFLNHSENATAKDIAPTLTLYVGKNQLVEIEKVVLHPERSVVDIGLIKLKQKVLVTEKVMPICLPSKDYVAPGRMGYVSGWGRNVNFRFTERLKYVMLPVADQEKCELHYEKSTVPEKKGAVSPVGVQPILNKHTFCAGLTKYEEDTCYGDAGSAFAVHDTEEDTWYAAGILSFDKSCAVAEYGVYVRATDLKDWVQETMAK
Sequence Length
347
Preparation and Storage
Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.
SDS-PAGE
SDS-PAGE
Related Product Information for HP recombinant protein
As a result of holysis, hoglobin is found to accumulate in the kidney and is secreted in the urine. Haptoglobin captures, and combines with free plasma hoglobin to allow hepatic recycling of he iron and to prevent kidney damage. Haptoglobin also acts as an antioxidant, has antibacterial activity and plays a role in modulating many aspects of the acute phase response. Hoglobin/haptoglobin complexes are rapidely cleared by the macrophage CD163 scavenger receptor expressed on the surface of liver Kupfer cells through an endocytic lysosomal degradation pathway. Uncleaved haptoglogin, also known as zonulin, plays a role in intestinal permeability, allowing intercellular tight junction disassembly, and controlling the equilibrium between tolerance and immunity to non-self antigens.
Product Categories/Family for HP recombinant protein
References
Structure, hormonal regulation, and identification of the interleukin-6- and dexamethasone-responsive element of the rat haptoglobin gene.Marinkovic S., Baumann H.Mol. Cell. Biol. 10:1573-1583(1990) Liver regeneration after PH.Xu C.S., Li W.Q., Li Y.C., Ma H., Wang L., Wang S.F., Han H.P., Wang G.P., Chai L.Q., Yuan J.Y., Yang K.J., Yan H.M., Chang C.F., Zhao L.F., Shi J.B., Rahman S., Wang Q.N., Zhang J.B. Nucleotide sequence of rat haptoglobin cDNA. Characterization of the alpha beta-subunit junction region of prohaptoglobin.Goldstein L.A., Heath E.C.J. Biol. Chem. 259:9212-9217(1984) Biosynthesis and processing of rat haptoglobin.Hanley J.M., Haugen T.H., Heath E.C.J. Biol. Chem. 258:7858-7869(1983) Comparative sequence analysis of the N-terminal region of rat, rabbit, and dog haptoglobin beta-chains.Kurosky A., Kim H.H., Touchstone B.Comp. Biochem. Physiol. 55B:453-459(1976) Lubec G., Afjehi-Sadat L.Submitted (DEC-2006) to UniProtKB
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
40.5 kDa
NCBI Official Full Name
haptoglobin
NCBI Official Synonym Full Names
haptoglobin
NCBI Official Symbol
Hp
NCBI Official Synonym Symbols
Ba1-647
NCBI Protein Information
haptoglobin
UniProt Protein Name
Haptoglobin
UniProt Gene Name
Hp
UniProt Entry Name
HPT_RAT
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Product Notes
The HP hp (Catalog #AAA116206) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 19-346aa; Partial. The amino acid sequence is listed below: VELGNDATDI EDDSCPKPPE IANGYVEHLV RYRCRQFYKL QTEGDGIYTL NSEKQWVNPA AGDKLPKCEA VCGKPKHPVD QVQRIIGGSM DAKGSFPWQA KMISRHGLTT GATLISDQWL LTTAQNLFLN HSENATAKDI APTLTLYVGK NQLVEIEKVV LHPERSVVDI GLIKLKQKVL VTEKVMPICL PSKDYVAPGR MGYVSGWGRN VNFRFTERLK YVMLPVADQE KCELHYEKST VPEKKGAVSP VGVQPILNKH TFCAGLTKYE EDTCYGDAGS AFAVHDTEED TWYAAGILSF DKSCAVAEYG VYVRATDLKD WVQETMAK. It is sometimes possible for the material contained within the vial of "Haptoglobin protein, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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