IHC (Immunohistochemistry)
(Formalin-fixed, paraffin-embedded human liver stained with Haptoglobin Mouse Monoclonal Antibody (HP/3839) at 2ug/ml.)
Mouse anti-Human Haptoglobin (HP) Monoclonal Antibody | anti-HP antibody
Haptoglobin (HP) Mouse Monoclonal Antibody [Clone HP/3839]
Gene Names
HP; BP; HPA1S; HP2ALPHA2
Reactivity
Human
Applications
Immunohistochemistry
Synonyms
Haptoglobin (HP), Antibody; Haptoglobin (HP) Mouse Monoclonal Antibody [Clone HP/3839]; Binding peptide (BP); Haptoglobin alpha chain/alpha(1S) beta; Haptoglobin alpha(2FS) beta; Haptoglobin beta chain; Haptoglobin, alpha polypeptide; Haptoglobin, beta polypeptide; HP; HP2 ALPHA2; HPA1S; HPT; MGC111141; Zonulin; anti-HP antibody
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
Mouse/IgG1, kappa
Clone Number
HP/3839
Form/Format
200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0. 05% BSA & 0. 05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Concentration
Purified Ab with BSA and Azide at 200ug/ml
OR
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml (varies by lot)
OR
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml (varies by lot)
Applicable Applications for anti-HP antibody
IHC (Immunohistochemistry)
Immunogen
Recombinant fragment (around aa100-250) of human HP protein (exact sequence is proprietary)
Cellular Localization
Secreted. Selective granular cytoplasmic expression in liver with distinct positivity in plasma and extracellular matrix
Positive Control
Human liver.
Hu-chromosome Location
16q22.2
Unigene
513711; 702099
Preparation and Storage
Antibody with azide: store at 2 to 8 degree C
Antibody without azide: store at -20 to -80 degree C
Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Antibody without azide: store at -20 to -80 degree C
Antibody is stable for 24 months. Non-hazardous. No MSDS required.
IHC (Immunohistochemistry)
(Formalin-fixed, paraffin-embedded human liver stained with Haptoglobin Mouse Monoclonal Antibody (HP/3839) at 2ug/ml.)
IHC (Immunohistochemistry)
(Formalin-fixed, paraffin-embedded human liver stained with Haptoglobin Mouse Monoclonal Antibody (HP/3839) at 2ug/ml.)
Related Product Information for anti-HP antibody
Haptoglobin (Hp) is a blood plasma protein that functions to bind free Hemoglobin that has been released from erythrocytes, thereby inhibiting its oxidative activity. During this process, Haptoglobin sequesters the iron within Hemoglobin, preventing iron-utilizing bacteria from benefitting from hemolysis. This function suggests that Haptoglobin concentrations may increase in response to inflammation. The resulting Haptoglobin-Hemoglobin complex is then removed by the reticulo-endothelial system. Due to cleavage of a common precursor protein during protein synthesis, Haptoglobin consists of two a and two b chains, connected by disulfide bridges. In human, Haptoglobin exists in two allelic forms designated Haptoglobin 1 (Hp1) and Haptoglobin 2 (Hp2), where Hp2 is the result of a partial Hp1 gene duplication. There are three known phenotypes of human Haptoglobin: Hp1-1, Hp2-1 and Hp2-2, which may be associated with diabetes and cardiovascular disease pathology and a susceptibility to Parkinson s and Crohn s disease. Haptoglobin levels are useful in identifying hemolytic anemia, the abnormal breakdown of red blood cells. Haptoglobin is expressed in mammalian hepatocytes as well as other tissues such as skin, lung and kidney.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
45,205 Da
NCBI Official Full Name
haptoglobin
NCBI Official Synonym Full Names
haptoglobin
NCBI Official Symbol
HP
NCBI Official Synonym Symbols
BP; HPA1S; HP2ALPHA2
NCBI Protein Information
haptoglobin; zonulin; binding peptide; haptoglobin alpha(1S)-beta; haptoglobin alpha(2FS)-beta; haptoglobin, beta polypeptide; haptoglobin, alpha polypeptide
UniProt Protein Name
Haptoglobin
UniProt Gene Name
HP
UniProt Entry Name
HPT_HUMAN
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Product Notes
The HP hp (Catalog #AAA215706) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Haptoglobin (HP) Mouse Monoclonal Antibody [Clone HP/3839] reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Haptoglobin (HP) can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry). Researchers should empirically determine the suitability of the HP hp for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Haptoglobin (HP), Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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