Human 15-Hydroxyprostaglandin Dehydrogenase [Nad, HPGD ELISA Kit | HPGD elisa kit
Human 15-Hydroxyprostaglandin Dehydrogenase [Nad, HPGD Primacu ELISA Kit
Gene Names
HPGD; PGDH; PGDH1; PHOAR1; 15-PGDH; SDR36C1
Reactivity
Human
Synonyms
15-Hydroxyprostaglandin Dehydrogenase [Nad, HPGD; N/A; Human 15-Hydroxyprostaglandin Dehydrogenase [Nad, HPGD Primacu ELISA Kit; 15-hydroxyprostaglandin dehydrogenase [NAD; 15-PGDH; PGDH1; SDR36C1; HPGD elisa kit
Reactivity
Human
Assay Type
Sandwich
Samples
Serum, plasma, cell culture supernates
Detection Range
31.25-2000pg/mL
Sensitivity
6.44pg/mL
Standard Solution
20ng/mL
Assay Time
3.5h
Preparation and Storage
Store at 2-8 degree C
Related Product Information for HPGD elisa kit
15-hydroxyprostaglandin dehydrogenase [NAD+], also known as Prostaglandin dehydrogenase 1, HPGD, and PGDH1, is a member of the short-chain dehydrogenases/reductases (SDR) family. Prostaglandins (PGs) play a key role in the onset of labor in many species and regulate uterine contractility and cervical dilatation. Therefore, the regulation of prostaglandin output by PG synthesizing and metabolizing enzymes in the human myometrium may determine uterine activity patterns in human labor both at preterm and at term. Prostaglandin dehydrogenase (PGDH) metabolizes prostaglandins (PGs) to render them inactive. HPGD is down-regulated by cortisol, dexamethasone, and betamethasone and down-regulated in colon cancer. It is up-regulated by TGFB1. HPGD contributes to the regulation of events that are under the control of prostaglandin levels. HPGD catalyzes the NAD-dependent dehydrogenation of lipoxin A4 to form 15-oxo-lipoxin A4. and inhibits in vivo proliferation of colon cancer cells. Defects in HPGD are the cause of primary hypertrophic osteoarthropathy autosomal recessive (PHOAR), cranio-osteoarthropathy (COA), and isolated congenital nail clubbing.
Product Categories/Family for HPGD elisa kit
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
21,526 Da
NCBI Official Full Name
15-hydroxyprostaglandin dehydrogenase
NCBI Official Synonym Full Names
hydroxyprostaglandin dehydrogenase 15-(NAD)
NCBI Official Symbol
HPGD
NCBI Official Synonym Symbols
PGDH; PGDH1; PHOAR1; 15-PGDH; SDR36C1
NCBI Protein Information
15-hydroxyprostaglandin dehydrogenase [NAD(+)]; 15-hydroxyprostaglandin dehydrogenase [NAD(+)]; NAD+-dependent 15-hydroxyprostaglandin dehydrogenase; prostaglandin dehydrogenase 1; short chain dehydrogenase/reductase family 36C, member 1
UniProt Protein Name
15-hydroxyprostaglandin dehydrogenase [NAD(+)]
UniProt Gene Name
HPGD
UniProt Synonym Gene Names
PGDH1; 15-PGDH
UniProt Entry Name
PGDH_HUMAN
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Product Notes
The Human HPGD hpgd (Catalog #AAA124265) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA124265 ELISA Kit recognizes Human HPGD. It is sometimes possible for the material contained within the vial of "15-Hydroxyprostaglandin Dehydrogenase [Nad, HPGD, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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