Standard Curve (Sample)
(Typical Testing Data/Standard Curve (for reference only))
Human Calcium And Integrin-Binding Family Member 2, CIB2 ELISA Kit | CIB2 elisa kit
Human Calcium And Integrin-Binding Family Member 2, CIB2 Primacu ELISA Kit
Gene Names
CIB2; KIP2; USH1J; DFNB48
Reactivity
Human
Synonyms
Calcium And Integrin-Binding Family Member 2, CIB2; N/A; Human Calcium And Integrin-Binding Family Member 2, CIB2 Primacu ELISA Kit; Calcium and integrin-binding family member 2; CIB2; KIP2; CIB2 elisa kit
Reactivity
Human
Assay Type
Sandwich
Samples
Serum, plasma, cell culture supernates
Detection Range
15.63-1000pg/mL
Sensitivity
5.6pg/mL
Standard Solution
10ng/mL
Assay Time
3.5h
Preparation and Storage
Store at 2-8 degree C
Standard Curve (Sample)
(Typical Testing Data/Standard Curve (for reference only))
Standard Curve (Sample)
(Typical Testing Data/Standard Curve (for reference only))
Related Product Information for CIB2 elisa kit
Calcium and integrin-binding protein 2 (CIB2) belongs to a protein family with four known members, CIB1 through CIB4, which are characterized by multiple calcium-binding EF-hand domains. Sensorineural hearing loss is genetically heterogeneous. The mutations in CIB2, which encodes a calcium- and integrin-binding protein, are associated with nonsyndromic deafness (DFNB48) and Usher syndrome type 1J (USH1J). Furthermore, in zebrafish and Drosophila melanogaster, CIB2 is essential for the function and proper development of hair cells and retinal photoreceptor cells. We also show that CIB2 is a new member of the vertebrate Usher interactome. Variants in CIB2 can underlie either Usher syndrome type I (USH1J) or nonsyndromic hearing impairment (NSHI)(DFNB48). CIB2 is widely expressed in various human and animal tissues, mainly in skeletal muscle, nervous tissue, inner ear, and retina. The CIB2 protein is responsible for maintaining Ca(2+) homeostasis in cells and interacting with integrins-transmembrane receptors essential for cell adhesion, migration, and activation of signaling pathways. Calcium signaling pathway is crucial for signal transduction in the inner ear, and integrins regulate hair cell differentiation and maturation of the stereocilia.
Product Categories/Family for CIB2 elisa kit
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
21,644 Da
NCBI Official Full Name
calcium and integrin-binding family member 2 isoform 1
NCBI Official Synonym Full Names
calcium and integrin binding family member 2
NCBI Official Symbol
CIB2
NCBI Official Synonym Symbols
KIP2; USH1J; DFNB48
NCBI Protein Information
calcium and integrin-binding family member 2; KIP 2; 2810434I23Rik; Usher syndrome 1J (autosomal recessive); DNA-dependent protein kinase catalytic subunit-interacting protein 2
UniProt Protein Name
Calcium and integrin-binding family member 2
UniProt Gene Name
CIB2
UniProt Synonym Gene Names
KIP2; KIP 2
UniProt Entry Name
CIB2_HUMAN
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Product Notes
The Human CIB2 cib2 (Catalog #AAA124337) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA124337 ELISA Kit recognizes Human CIB2. It is sometimes possible for the material contained within the vial of "Calcium And Integrin-Binding Family Member 2, CIB2, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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