Standard Curve (Sample)
(Typical Testing Data/Standard Curve (for reference only))
Human Complement Decay-Accelerating Factor, CD55 ELISA Kit | CD55 elisa kit
Human Complement Decay-Accelerating Factor, CD55 Primacu ELISA Kit
Gene Names
CD55; CR; TC; DAF; CROM
Reactivity
Human
Synonyms
Complement Decay-Accelerating Factor, CD55; N/A; Human Complement Decay-Accelerating Factor, CD55 Primacu ELISA Kit; Complement decay-accelerating factor; CD55; CR; DAF; CD55 elisa kit
Reactivity
Human
Assay Type
Sandwich
Samples
Serum, plasma, cell culture supernates
Detection Range
23.44-1500pg/mL
Sensitivity
4.59pg/mL
Standard Solution
15ng/mL
Assay Time
3.5h
Preparation and Storage
Store at 2-8 degree C
Standard Curve (Sample)
(Typical Testing Data/Standard Curve (for reference only))
Standard Curve (Sample)
(Typical Testing Data/Standard Curve (for reference only))
Related Product Information for CD55 elisa kit
CD55, also well known as decay-accelerating factor (DAF), is a member of the RCA (regulators of complement activation) family characterized by four to 30 SCRs (short consensus repeats) in their plasma-exposed regions. It is a major regulator of the alternative and classical pathways of complement activation and is expressed on all serum-exposed cells. CD55 is physiologically acting as an inhibitor of the complement system, but is also broadly expressed in malignant tumours. DAF seems to exert different functions beyond its immunological role such as promotion of tumorigenesis, decrease of complement mediated tumor cell lysis, autocrine loops for cell rescue and evasion of apoptosis, neoangiogenesis, invasiveness, cell motility. It is commonly hijacked by invading pathogens, including many enteroviruses and uropathogenic Escherichia coli, to promote cellular attachment prior to infection. This 70-75 kDa glycoprotein CD55 containing four SCR modules is involved in the regulation of the complement cascade. It inhibits complement activation by suppressing the function of C3/C5 convertases, thereby limiting local generation or deposition of C3a/C5a and membrane attack complex (MAC or C5b-9) production. DAF has been identified as a ligand for an activation-associated, seven-transmembrane lymphocyte receptor, CD97, which is a receptor mediating attachment and infection of several viruses and bacteria. In addition, it has been shown that DAF regulates the interplay between complement and T cell immunity in vivo, and thus may be implicated in immune and tumor biology.
Product Categories/Family for CD55 elisa kit
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
41,400 Da
NCBI Official Full Name
complement decay-accelerating factor isoform 1 preproprotein
NCBI Official Synonym Full Names
CD55 molecule, decay accelerating factor for complement (Cromer blood group)
NCBI Official Symbol
CD55
NCBI Official Synonym Symbols
CR; TC; DAF; CROM
NCBI Protein Information
complement decay-accelerating factor; CD55 antigen
UniProt Protein Name
Complement decay-accelerating factor
UniProt Gene Name
CD55
UniProt Synonym Gene Names
CR; DAF
UniProt Entry Name
DAF_HUMAN
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Product Notes
The Human CD55 cd55 (Catalog #AAA124292) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA124292 ELISA Kit recognizes Human CD55. It is sometimes possible for the material contained within the vial of "Complement Decay-Accelerating Factor, CD55, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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