Standard Curve (Sample)
(This standard curve is only for demonstration purposes. A standard curve should be generated for each assay.)
Human HE4/WFDC2/WAP5 ELISA Kit | HE4/WFDC2/WAP5 elisa kit
Human HE4/WFDC2/WAP5 ELISA Kit
Reactivity
Human
Synonyms
HE4/WFDC2/WAP5; N/A; Human HE4/WFDC2/WAP5 ELISA Kit; HE4 ELISA Kit, Human; WAP four-disulfide core domain 2; dJ461P17.6 ELISA Kit, Human; EDDM4 ELISA Kit, Human; WAP5 ELISA Kit, Human; HE4/WFDC2/WAP5 elisa kit
Reactivity
Human
Specificity
For the quantitative determination of Human HE4/WFDC2/WAP5 concentration in serum.
Assay Type
Solid Phase Sandwich ELISA (quantitative)
Sample Types
Serum
Detection Range
31.25-2000pg/mL
Sensitivity
6.57pg/mL
Conjugation
HRP
Materials Provided
1. 96 well microplate coated with Capture Antibody
2. Detection Antibody conjugated to HRP
3. Standards
4. Wash Buffer Concentrate
5. Dilution Buffer Concentrate
6. Color Reagent A
7. Color Reagent B
8. Stop Solution
2. Detection Antibody conjugated to HRP
3. Standards
4. Wash Buffer Concentrate
5. Dilution Buffer Concentrate
6. Color Reagent A
7. Color Reagent B
8. Stop Solution
Standard Curve (Sample)
(This standard curve is only for demonstration purposes. A standard curve should be generated for each assay.)
Standard Curve (Sample)
(This standard curve is only for demonstration purposes. A standard curve should be generated for each assay.)
Related Product Information for HE4/WFDC2/WAP5 elisa kit
This HE4 ELISA Kit, Human is an enzyme-linked immunosorbent assay for the quantitative measurement of Human HE4 protein in Serum. It contains recombinant Human HE4, and antibodies raised against the recombinant protein. This ELISA kit is complete and ready-to-use.
Background: WAP four-disulfide core domain protein 2, also known as Epididymal secretory protein E4, Major epididymis-specific protein E4, Putative protease inhibitor WAP5, WFDC2 and HE4, is a secreted protein that contains two WAP domains. WFDC2/HE4 is a member of a family of stable 4-disulfide core proteins that are secreted at high levels. It is expressed in a number of normal tissues, including male reproductive system, regions of the respiratory tract and nasopharynx. It is highly expressed in a number of tumors cells lines, such ovarian, colon, breast, lung and renal cells lines. Initially described as being exclusively transcribed in the epididymis. WFDC2 may be a component of the innate immune defences of the lung, nasal and oral cavities and suggest that WFDC2 functions in concert with related WAP domain containing proteins in epithelial host defence. WFDC2 re-expression in lung carcinomas may prove to be associated with tumour type and should be studied in further detail. Mammary gland expression of tammar WFDC2 during the course of lactation showed WFDC2 was elevated during pregnancy, reduced in early lactation and absent in mid-late lactation. WFDC2/HE4 can undergo a complex series of alternative splicing events that can potentially yield five distinct WAP domain containing protein isoforms.
Background: WAP four-disulfide core domain protein 2, also known as Epididymal secretory protein E4, Major epididymis-specific protein E4, Putative protease inhibitor WAP5, WFDC2 and HE4, is a secreted protein that contains two WAP domains. WFDC2/HE4 is a member of a family of stable 4-disulfide core proteins that are secreted at high levels. It is expressed in a number of normal tissues, including male reproductive system, regions of the respiratory tract and nasopharynx. It is highly expressed in a number of tumors cells lines, such ovarian, colon, breast, lung and renal cells lines. Initially described as being exclusively transcribed in the epididymis. WFDC2 may be a component of the innate immune defences of the lung, nasal and oral cavities and suggest that WFDC2 functions in concert with related WAP domain containing proteins in epithelial host defence. WFDC2 re-expression in lung carcinomas may prove to be associated with tumour type and should be studied in further detail. Mammary gland expression of tammar WFDC2 during the course of lactation showed WFDC2 was elevated during pregnancy, reduced in early lactation and absent in mid-late lactation. WFDC2/HE4 can undergo a complex series of alternative splicing events that can potentially yield five distinct WAP domain containing protein isoforms.
References
Bingle, L. et al., 2002, Oncogene. 21 (17):2768-73.
Hellström, I. et al., 2003, Cancer Res. 63 (13):3695-700.
Bingle, L. et al., 2006, Respir Res. 7 : 61.
Galgano, M.T. et al., 2006, Mod Pathol.19 (6):847-53.
Sharp, J.A. et al., 2007, Evol Dev. 9 (4): 378-92.
Hellström, I. et al., 2003, Cancer Res. 63 (13):3695-700.
Bingle, L. et al., 2006, Respir Res. 7 : 61.
Galgano, M.T. et al., 2006, Mod Pathol.19 (6):847-53.
Sharp, J.A. et al., 2007, Evol Dev. 9 (4): 378-92.
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Product Notes
The Human HE4/WFDC2/WAP5 (Catalog #AAA258450) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA258450 ELISA Kit recognizes Human HE4/WFDC2/WAP5. It is sometimes possible for the material contained within the vial of "HE4/WFDC2/WAP5, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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