Standard Curve (Sample)
(Typical Testing Data/Standard Curve (for reference only))
Human Intercellular Adhesion Molecule 3, ICAM3 ELISA Kit | ICAM3 elisa kit
Human Intercellular Adhesion Molecule 3, ICAM3 Primacu ELISA Kit
Gene Names
ICAM3; CD50; CDW50; ICAM-R
Reactivity
Human
Synonyms
Intercellular Adhesion Molecule 3, ICAM3; N/A; Human Intercellular Adhesion Molecule 3, ICAM3 Primacu ELISA Kit; Intercellular adhesion molecule 3; CD50; ICAM3 elisa kit
Reactivity
Human
Assay Type
Sandwich
Samples
Serum, plasma, cell culture supernates
Detection Range
62.5-4000pg/mL
Sensitivity
17.17pg/mL
Standard Solution
40ng/mL
Assay Time
3.5h
Preparation and Storage
Store at 2-8 degree C
Standard Curve (Sample)
(Typical Testing Data/Standard Curve (for reference only))
Standard Curve (Sample)
(Typical Testing Data/Standard Curve (for reference only))
Related Product Information for ICAM3 elisa kit
The protein ICAM-3, also known as CD50, is a member of the intercellular adhesion molecule (ICAM) family consisting of three members. It is a DC-SIGN ligand that is constitutively expressed on resting leukocytes and is thus an important molecule for the first immune response. ICAM-3 comprises five immunoglobulin-like domains and binds LFA-1 through its two N-terminal domains. It functions not only as an adhesion molecule but also as a potent signaling molecule. ICAM-3 binds to LFA-1 on antigen-presenting cells (APC) stabilizing the T cell-APC interaction, facilitating signaling through the CD3/TCR complex. However, recent evidence using cultured and transformed T cells suggests ICAM-3 may also function in signaling. It has been reported that the CD50 molecule can play a role in developing functionally mature T lymphocytes and its expression increases during the maturation process of T lymphocytes. Also, the interactions of ICAM-3 and LFA-1 facilitate HIV-1- induced virological synapse formation between T cells. ICAM-3 is associated with an increase in cellular radio-resistance and cancer cell proliferation. It could be considered as a candidate for anti-cancer drug development and as a cancer test marker.
Product Categories/Family for ICAM3 elisa kit
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
59,541 Da
NCBI Official Full Name
intercellular adhesion molecule 3
NCBI Official Synonym Full Names
intercellular adhesion molecule 3
NCBI Official Symbol
ICAM3
NCBI Official Synonym Symbols
CD50; CDW50; ICAM-R
NCBI Protein Information
intercellular adhesion molecule 3; ICAM-3; intercellular adhesion molecule-3
UniProt Protein Name
Intercellular adhesion molecule 3
UniProt Gene Name
ICAM3
UniProt Synonym Gene Names
ICAM-3
UniProt Entry Name
ICAM3_HUMAN
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Product Notes
The Human ICAM3 icam3 (Catalog #AAA124162) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA124162 ELISA Kit recognizes Human ICAM3. It is sometimes possible for the material contained within the vial of "Intercellular Adhesion Molecule 3, ICAM3, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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