SDS-PAGE
(SDS-PAGE Analysis Purified CD50 Recombinant Mouse Monoclonal Antibody (rICAM3/1019). Confirmation of Purity and Integrity of Antibody.)
Mouse anti-Human CD50/ICAM3 Monoclonal Antibody | anti-ICAM3 antibody
CD50/ICAM3
Gene Names
ICAM3; CD50; CDW50; ICAM-R
Reactivity
Human
Applications
Immunohistochemistry
Purity
Purified Ab with BSA and Azide at 200ug/ml or Purified Ab with BSA and Azide at 200ug/ml or Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
Synonyms
CD50/ICAM3, Antibody; CD50/ICAM3; ICAMR; Intercellular adhesion molecule 3 (ICAM3); anti-ICAM3 antibody
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG1, kappa
Clone Number
rICAM3/1019
Specificity
Recognizes the D1 domain of an N-glycosylated glycoprotein of 120kDa with intra-chain disulfide bonds, identified as CD50 or ICAM-3 (Leucocyte Workshop VI). CD50 is the major ligand for LFA-1 (CD11a/CD18) and may have signaling role to increase adhesion. It is expressed on thymocytes and T lymphocytes and is resistant to treatment with phosphatidylinositol (PI) phospholipase C. This MAb is excellent for staining of formalin/paraffin tissues.
Purity/Purification
Purified Ab with BSA and Azide at 200ug/ml or Purified Ab with BSA and Azide at 200ug/ml or Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
Form/Format
200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Sequence Length
547
Applicable Applications for anti-ICAM3 antibody
IHC (Immunohistochemistry)
Immunogen
Recombinant full-length Human ICAM3 protein
Cellular Localization
Cell Surface
Antibody Type
Recombinant Antibody
Hu-chromosome Location
19p13.2
Positive Control
HL-60 or THP-1 cells. Human Lymph node or Tonsil.
Preparation and Storage
Antibody with azide: store at 2 to 8 degree C.
Antibody without azide: store at -20 to -80 degree C.
Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Antibody without azide: store at -20 to -80 degree C.
Antibody is stable for 24 months. Non-hazardous. No MSDS required.
SDS-PAGE
(SDS-PAGE Analysis Purified CD50 Recombinant Mouse Monoclonal Antibody (rICAM3/1019). Confirmation of Purity and Integrity of Antibody.)
SDS-PAGE
(SDS-PAGE Analysis Purified CD50 Recombinant Mouse Monoclonal Antibody (rICAM3/1019). Confirmation of Purity and Integrity of Antibody.)
IHC (Immunohistochemistry)
(Formalin-fixed, paraffin-embedded human Tonsil stained with CD50 Recombinant Mouse Monoclonal Antibody (rICAM3/1019).)
IHC (Immunohistochemistry)
(Formalin-fixed, paraffin-embedded human Tonsil stained with CD50 Recombinant Mouse Monoclonal Antibody (rICAM3/1019).)
References
Leukocyte Typing V (S.F. Schlossman, et al, eds.) Oxford University Press, Oxford (1995) p. 1546-1547, 1578-1579. | C.L. Holness, et al, (1995) J Biol Chem 270: 877-884. | Y. van Kooyk, et al, (1996) J Exp Med 183: 1247-1252. | Leukocyte Typing VI (T. Kishimoto, et al, eds.) Garland Publishing, Inc., New York (1997) p. 403-409.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
110-160kDa
NCBI Official Full Name
intercellular adhesion molecule 3 isoform 1
NCBI Official Synonym Full Names
intercellular adhesion molecule 3
NCBI Official Symbol
ICAM3
NCBI Official Synonym Symbols
CD50; CDW50; ICAM-R
NCBI Protein Information
intercellular adhesion molecule 3
UniProt Protein Name
Intercellular adhesion molecule 3
UniProt Gene Name
ICAM3
UniProt Synonym Gene Names
ICAM-3
UniProt Entry Name
ICAM3_HUMAN
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Product Notes
The ICAM3 icam3 (Catalog #AAA215418) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The CD50/ICAM3 reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CD50/ICAM3 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry). Researchers should empirically determine the suitability of the ICAM3 icam3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CD50/ICAM3, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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