Application Data
(This assay recognizes recombinant human SLAMF6. The factors listed above were prepared at 50ng/mL in dilution buffer and assayed for cross-reactivity. No cross-reactivity was observed.Preparations of SH2D1A at 10ng/mL in a mid-range recombinant human SLAMF6 control were assayed for interference. No significant interference was observed.)
Human Ly108/SLAMF6 ELISA Kit | Ly108/SLAMF6 elisa kit
Human Ly108/SLAMF6 ELISA Kit
Reactivity
Human
Synonyms
Ly108/SLAMF6; N/A; Human Ly108/SLAMF6 ELISA Kit; SLAMF6 ELISA Kit, Human; SLAM family member 6; CD352 ELISA Kit, Human; KALI ELISA Kit, Human; KALIb ELISA Kit, Human; Ly108 ELISA Kit, Human; NTB-A ELISA Kit, Human; NTBA ELISA Kit, Human; SF2000 ELISA Kit, Human; Ly108/SLAMF6 elisa kit
Reactivity
Human
Specificity
The kit has been verified by high purity Human Ly108/SLAMF6 recombinant protein.
Assay Type
Solid Phase Sandwich ELISA (quantitative)
Sample Types
Recombinant protein
Detection Range
15.63-1000pg/mL
Sensitivity
12.7pg/mL
Conjugation
HRP
Interference
Preparations of SH2D1A at 10ng/mL in a mid-range recombinant human SLAMF6 control were assayed for interference. No significant interference was observed.
Materials Provided
1. 96 well microplate coated with Capture Antibody
2. Detection Antibody conjugated to HRP
3. Standards
4. Wash Buffer Concentrate
5. Dilution Buffer Concentrate
6. Color Reagent A
7. Color Reagent B
8. Stop Solution
2. Detection Antibody conjugated to HRP
3. Standards
4. Wash Buffer Concentrate
5. Dilution Buffer Concentrate
6. Color Reagent A
7. Color Reagent B
8. Stop Solution
Application Data
(This assay recognizes recombinant human SLAMF6. The factors listed above were prepared at 50ng/mL in dilution buffer and assayed for cross-reactivity. No cross-reactivity was observed.Preparations of SH2D1A at 10ng/mL in a mid-range recombinant human SLAMF6 control were assayed for interference. No significant interference was observed.)
Application Data
(This assay recognizes recombinant human SLAMF6. The factors listed above were prepared at 50ng/mL in dilution buffer and assayed for cross-reactivity. No cross-reactivity was observed.Preparations of SH2D1A at 10ng/mL in a mid-range recombinant human SLAMF6 control were assayed for interference. No significant interference was observed.)
Standard Curve (Sample)
(This standard curve is only for demonstration purposes. A standard curve should be generated for each assay.)
Standard Curve (Sample)
(This standard curve is only for demonstration purposes. A standard curve should be generated for each assay.)
Related Product Information for Ly108/SLAMF6 elisa kit
This SLAMF6 ELISA Kit, Human is an enzyme-linked immunosorbent assay for the quantitative measurement of Human SLAMF6 protein in Recombinant protein. It contains recombinant Human SLAMF6, and antibodies raised against the recombinant protein. This ELISA kit is complete and ready-to-use.
Background: SLAM family member 6, also known as Activating NK receptor, NK-T-B-antigen, NTB-A, SLAMF6, KALI and Ly18, is a single-pass type I membrane protein that belongs to the CD2 subfamily of the immunoglobulin superfamily. SLAMF6/Ly18 contains one Ig-like (immunoglobulin-like) domain. It is expressed by all (resting and activated) natural killer cells (NK), T- and B-lymphocytes. SLAMF6/Ly18 triggers cytolytic activity only in natural killer cells (NK) expressing high surface densities of natural cytotoxicity receptors. SLAMF6/Ly18 is a homodimer. It interacts with PTN6 and, upon phosphorylation, with PTN11 and SH2D1A/SAP. SLAMF6/Ly18 undergoes tyrosine phosphorylation and associates with the Src homology 2 domain-containing protein (SH2D1A) as well as with SH2 domain-containing phosphatases (SHPs). It may function as a coreceptor in the process of NK cell activation. SLAMF6/Ly18 can also mediate inhibitory signals in NK cells from X-linked lymphoproliferative patients.
Background: SLAM family member 6, also known as Activating NK receptor, NK-T-B-antigen, NTB-A, SLAMF6, KALI and Ly18, is a single-pass type I membrane protein that belongs to the CD2 subfamily of the immunoglobulin superfamily. SLAMF6/Ly18 contains one Ig-like (immunoglobulin-like) domain. It is expressed by all (resting and activated) natural killer cells (NK), T- and B-lymphocytes. SLAMF6/Ly18 triggers cytolytic activity only in natural killer cells (NK) expressing high surface densities of natural cytotoxicity receptors. SLAMF6/Ly18 is a homodimer. It interacts with PTN6 and, upon phosphorylation, with PTN11 and SH2D1A/SAP. SLAMF6/Ly18 undergoes tyrosine phosphorylation and associates with the Src homology 2 domain-containing protein (SH2D1A) as well as with SH2 domain-containing phosphatases (SHPs). It may function as a coreceptor in the process of NK cell activation. SLAMF6/Ly18 can also mediate inhibitory signals in NK cells from X-linked lymphoproliferative patients.
References
Gray CW. et al., 2000, Eur J Biochem. 267 (18): 5699-710.
Bottino C. et al., 2001, J Exp Med. 194 (3): 235-46.
Valdez PA. et al., 2004, J Biol Chem. 279 (18): 18662-9.
Claus M. et al., 2007, Front Biosci. 13: 956-65.
Bottino C. et al., 2001, J Exp Med. 194 (3): 235-46.
Valdez PA. et al., 2004, J Biol Chem. 279 (18): 18662-9.
Claus M. et al., 2007, Front Biosci. 13: 956-65.
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Product Notes
The Human Ly108/SLAMF6 (Catalog #AAA258442) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA258442 ELISA Kit recognizes Human Ly108/SLAMF6. It is sometimes possible for the material contained within the vial of "Ly108/SLAMF6, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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