FCM/FACS (Flow Cytometry)
Mouse Ly108 Monoclonal Antibody | anti-Ly108 antibody
Ly108 antibody
Applications
Functional Assay, Immunohistochemistry, Flow Cytometry, Functional Assay
Purity
Ly108 antibody was purified by affinity chromatography.
Synonyms
Ly108, Antibody; Ly108 antibody; Monoclonal Ly108; Anti-Ly108; Ly-108; Ly108; CD antigen CD352; Lymphocyte antigen 108; SLAM Family Receptor; Ly 108; SLAM F6; SLAMF6; anti-Ly108 antibody
Host
Mouse
Clonality
Monoclonal
Isotype
IgG2a kappa
Clone Number
13G3-19D
Specificity
Mouse
Purity/Purification
Ly108 antibody was purified by affinity chromatography.
Form/Format
Liquid in TBS, pH 8.0, with 0.09% Sodium Azide
Concentration
0.5 mg/ml (varies by lot)
Sequence Length
351
Applicable Applications for anti-Ly108 antibody
FA (Functional Assay), IHC (Immunohistochemistry), FCM/FACS (Flow Cytometry)
Biological Significance
The 13G3-19D monoclonal antibody reacts with mouse Ly108, the mouse homologue of human SLAMF6. Mouse Ly108 is also known as NTB-A, and is expressed on NK, T cells, and B cells. Engagement of the Ly108 receptor enhances NK cell activity and expression of IFN-gamma, and contributes to the inability of NK cells to kill Epstein Barr virus-infected B cells in X-linked lymphoproliferative disease. CD4+ T cells from Ly108 knock-out mice exhibit diminished ability to produce IL-4 and defective neutrophil functions.Staining has not revealed any strain differences between C57BL/6 and BALB/c mice. Other strains have not been tested.
Cross Reactivity
Mouse
Preparation and Storage
Store at 4°C.
FCM/FACS (Flow Cytometry)
FCM/FACS (Flow Cytometry)
Related Product Information for anti-Ly108 antibody
Mouse monoclonal Ly108 antibody
Product Categories/Family for anti-Ly108 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI Official Full Name
Ly108
UniProt Protein Name
Ly108
UniProt Gene Name
Slamf6
UniProt Entry Name
Q18PJ0_MOUSE
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Product Notes
The Ly108 slamf6 (Catalog #AAA107267) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's Ly108 can be used in a range of immunoassay formats including, but not limited to, FA (Functional Assay), IHC (Immunohistochemistry), FCM/FACS (Flow Cytometry). Researchers should empirically determine the suitability of the Ly108 slamf6 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Ly108, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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