Standard Curve (Sample)
(Typical Testing Data/Standard Curve (for reference only))
Human Lymphokine-Activated Killer T-Cell-Originated Protein Kinase, PBK ELISA Kit | PBK elisa kit
Human Lymphokine-Activated Killer T-Cell-Originated Protein Kinase, PBK Primacu ELISA Kit
Gene Names
PBK; SPK; CT84; TOPK; Nori-3
Reactivity
Human
Synonyms
Lymphokine-Activated Killer T-Cell-Originated Protein Kinase, PBK; N/A; Human Lymphokine-Activated Killer T-Cell-Originated Protein Kinase, PBK Primacu ELISA Kit; Lymphokine-activated killer T-cell-originated protein kinase; PBK; TOPK; PBK elisa kit
Reactivity
Human
Assay Type
Sandwich
Samples
Serum, plasma, cell culture supernates
Detection Range
62.5-4000pg/mL
Sensitivity
21.19pg/mL
Standard Solution
40ng/mL
Assay Time
3.5h
Preparation and Storage
Store at 2-8 degree C
Standard Curve (Sample)
(Typical Testing Data/Standard Curve (for reference only))
Standard Curve (Sample)
(Typical Testing Data/Standard Curve (for reference only))
Related Product Information for PBK elisa kit
PDZ binding kinase (PBK), also known as TOPK (T-LAK cell-originated protein kinase), is a serine/threonine kinase related to the dual specific mitogen-activated protein kinase kinase (MAPKK) family, and has all the characteristic protein kinase subdomains and a C-terminal PDZ-binding T/SXV motif. PBK is expressed in the testis restrictedly expressed in outer cell layer of seminiferous tubules, as well as placenta. PBK may be enrolled in the activation of lymphoid cells and support testicular functions, with a suggested role in the process of spermatogenesis. This mitotic kinase phosphorylates MAP kinase p38 and seems to be active in mitosis. When phosphorylated, PBK forms a protein-protein interaction with tumor suppressor p53 (TP53), leading to TP53 destabilization and attenuation of G2/M checkpoint during doxorubicin-induced DNA damage. The expression level of PBK is thus upregulated in a variety of neoplasms including hematological malignancies.
Product Categories/Family for PBK elisa kit
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
36,085 Da
NCBI Official Full Name
lymphokine-activated killer T-cell-originated protein kinase
NCBI Official Synonym Full Names
PDZ binding kinase
NCBI Official Symbol
PBK
NCBI Official Synonym Symbols
SPK; CT84; TOPK; Nori-3
NCBI Protein Information
lymphokine-activated killer T-cell-originated protein kinase; PDZ-binding kinase; cancer/testis antigen 84; MAPKK-like protein kinase; serine/threonine protein kinase; T-LAK cell-originated protein kinase; spermatogenesis-related protein kinase
UniProt Protein Name
Lymphokine-activated killer T-cell-originated protein kinase
UniProt Gene Name
PBK
UniProt Synonym Gene Names
TOPK; CT84; SPK
UniProt Entry Name
TOPK_HUMAN
Similar Products
Product Notes
The Human PBK pbk (Catalog #AAA124167) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA124167 ELISA Kit recognizes Human PBK. It is sometimes possible for the material contained within the vial of "Lymphokine-Activated Killer T-Cell-Originated Protein Kinase, PBK, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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