Standard Curve (Sample)
Human Programmed Cell Death 4 (PDCD4) ELISA Kit | PDCD4 elisa kit
Human Programmed Cell Death 4 (PDCD4) ELISA Kit
Gene Names
PDCD4; H731
Reactivity
Human
Synonyms
Programmed Cell Death 4 (PDCD4); N/A; Human Programmed Cell Death 4 (PDCD4) ELISA Kit; PDCD4; RP11-348N5.4; H731; MGC33046; MGC33047; nuclear antigen H731; programmed cell death 4; PDCD4 elisa kit
Reactivity
Human
Sequence Length
469
Assay Type
Sandwich
Preparation and Storage
Store at 2-8 degree C.
Standard Curve (Sample)
Standard Curve (Sample)
Related Product Information for PDCD4 elisa kit
Principle of the Assay: Human Programmed Cell Death 4 (PDCD4) ELISA Kit employs a two-site sandwich ELISA to quantitate PDCD4 in samples. An antibody specific for PDCD4 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any PDCD4 present is bound by the immobilized antibody. After removing any unbound substances, HRP-Conjugated Human PDCD4 detection antibody is added to the wells. Following a wash to remove any unbound HRP reagent, a Chromogen solution is added to the wells and color develops in proportion to the amount of PDCD4 bound in the initial step. The color development is stopped and the intensity of the color is measured.
Background/Introduction: PDCD4 encodes a protein localized to the nucleus in proliferrating cells. Expression of this gene is modulated by cytokines in natural killer and T cells. The gene product is thought to play a role in apoptosis but the specific role has not yet been determined. Two transcripts encoding different isoforms have been identified. The decuded 458-amino acid protein has a calculated molecular mass of 50.6kD. PDCD4 is an acidic protein with characteristics of a nuclear nonhistone protein. It contains 2 overlapping GxGxxG nucleotide-binding motifs, which are characteristic of protein kinases, but it does not have a kinase catalytic domain. PDCD4 also has several putative serine and threonine phosphorylation sites.
Background/Introduction: PDCD4 encodes a protein localized to the nucleus in proliferrating cells. Expression of this gene is modulated by cytokines in natural killer and T cells. The gene product is thought to play a role in apoptosis but the specific role has not yet been determined. Two transcripts encoding different isoforms have been identified. The decuded 458-amino acid protein has a calculated molecular mass of 50.6kD. PDCD4 is an acidic protein with characteristics of a nuclear nonhistone protein. It contains 2 overlapping GxGxxG nucleotide-binding motifs, which are characteristic of protein kinases, but it does not have a kinase catalytic domain. PDCD4 also has several putative serine and threonine phosphorylation sites.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
programmed cell death protein 4 isoform 1
NCBI Official Synonym Full Names
programmed cell death 4
NCBI Official Symbol
PDCD4
NCBI Official Synonym Symbols
H731
NCBI Protein Information
programmed cell death protein 4
UniProt Protein Name
Programmed cell death protein 4
UniProt Gene Name
PDCD4
UniProt Synonym Gene Names
H731
UniProt Entry Name
PDCD4_HUMAN
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Product Notes
The Human PDCD4 pdcd4 (Catalog #AAA331446) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA331446 ELISA Kit recognizes Human PDCD4. It is sometimes possible for the material contained within the vial of "Programmed Cell Death 4 (PDCD4), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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