Human PTX3 ELISA Kit | PTX3 elisa kit

Human PTX3 ELISA Kit

Cat. Num. AAA105998

• Gene Names: PTX3; TSG-14; TNFAIP5
• Reactivity: Human
• Applications: ELISA
• Synonyms: PTX3; N/A; Human PTX3 ELISA Kit; TNFAIP5; TSG14; Pentraxin-related protein PTX3; Pentaxin-related protein PTX3; Tumor necrosis factor alpha-induced protein 5; TNF alpha-induced protein 5; Tumor necrosis factor-inducible gene 14 protein; TSG-14; PTX3 elisa kit

• Reactivity: Human
• Specificity: The Human PTX3 ELISA Kit allows for the detection and quantification of endogenous levels of natural and/or recombinant Human PTX3 proteins within the range of 312 pg/ml - 20000 pg/ml.
• Sequence Length: 381
• Samples: Cell Culture Supernatants, Serum, Plasma
• Assay Type: Quantitative Sandwich
• Sensitivity: <10 pg/ml.

• Applicable Applications for PTX3 elisa kit: ELISA (Sandwich ELISA)
• Preparation and Storage: Shipped and store at 4 degree C for 6 months, store at -20 degree C for one year. Avoid freeze/thaw cycles.

Standard Curve (Sample)

Related Product Information for PTX3 elisa kit

Principle of the Assay: MBS Human PTX3 ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of Human PTX3 in Cell Culture Supernatants, Serum, Plasma. This assay employs an antibody specific for Human PTX3 coated on a 96-well plate. Standards and samples are pipetted into the wells and PTX3 present in a sample is bound to the wells by the immobilized antibody. The wells are washed and biotinylated anti-Human PTX3 antibody is added. After washing away unbound biotinylated antibody, HRP-conjugated streptavidin is pipetted to the wells. The wells are again washed, a TMB substrate solution is added to the wells and color develops in proportion to the amount of PTX3 bound. The Stop Solution changes the color from blue to yellow, and the intensity of the color is measured at 450 nm.

Background: PTX3 (Pentraxin 3) is a member of the pentraxin superfamily. This super family characterized by cyclic multimeric structure. The PTX3 gene is mapped to 3q25.32. The predicted 381-amino acid PTX3 protein has homology to the pentraxin protein family. Significant levels of PTX3 were detected in plasma of neutropenic patients with systemic A. PTX3 is effective in preventing CMV infection and reactivation, as well as subsequent Aspergillus infection. PTX3 activates the classical pathway of complementactivation and facilitates pathogen recognition by macrophages and DCs.

NCBI and Uniprot Product Information

• NCBI GI #: 167900484
• NCBI GeneID: 5806
• NCBI Accession #: NP_002843.2
• NCBI GenBank Nucleotide #: NM_002852.3
• UniProt Accession #: P26022; Q38M82; B2R6T6
• Molecular Weight: 41,976 Da
• NCBI Official Full Name: pentraxin-related protein PTX3
• NCBI Official Synonym Full Names: pentraxin 3, long
• NCBI Official Symbol: PTX3
• NCBI Official Synonym Symbols: TSG-14; TNFAIP5
• NCBI Protein Information: pentraxin-related protein PTX3; pentraxin-3; TNF alpha-induced protein 5; pentaxin-related protein PTX3; tumor necrosis factor alpha-induced protein 5; tumor necrosis factor, alpha-induced protein 5; tumor necrosis factor-inducible protein TSG-14; tumor necrosis factor-inducible gene 14 protein; pentraxin-related gene, rapidly induced by IL-1 beta; pentaxin-related gene, rapidly induced by IL-1 beta, tumor necrosis factor, alpha-induced protein 5
• UniProt Protein Name: Pentraxin-related protein PTX3
• UniProt Gene Name: PTX3
• UniProt Synonym Gene Names: TNFAIP5; TSG14; TNF alpha-induced protein 5; TSG-14
• UniProt Entry Name: PTX3_HUMAN