Fibrinogen Native Protein | TNXB native protein

Fibrinogen protein

Cat. Num. AAA75204

• Gene Names: TNXB; XB; TNX; XBS; EDS3; HXBL; TENX; TN-X; VUR8; TNXB1; TNXB2; TNXBS
• Purity: > 40% by SDS-PAGE
• Synonyms: Fibrinogen; N/A; Fibrinogen protein; Native Fibrinogen protein; TNXB native protein

• Host: Human
• Purity/Purification: > 40% by SDS-PAGE
• Form/Format: Lyophilized at 5mg/ml in 20mM Tris, 150mM NaCl with NO PERSERVATIVES ADDED.
• Concentration: 5mg lyophilized (varies by lot)
• Sequence Length: 211

• Grade: Partial Pure
• Reconstitution: Reconstitute with 0.1 ml sterile deionized water and mix for 50 minutes.
• Biohazard Information: This product has been tested at serum donor level by an FDA approved methods and found negative for HIV1/2, HCV antibodies and Hepatitis B surface antigen. Since no test can offer complete assurance, handle with precaution.
• Contaminants: Immunoelectrophoresis at pH 8.6 with anti-human fibrinogen shows a single band.
• Source Note: Human plasma
• Protein Type: Native
• Biological Significance: Fibrinogen (factor I) is a soluble plasma glycoprotein, synthesised by the liver, that is converted by thrombin into fibrin during blood coagulation. This is achieved through processes in the coagulation cascade that activate the zymogen prothrombin to the serine protease thrombin, which is responsible for converting fibrinogen into fibrin.
• Note: SDS-gel electrophoresis (after reduction): Aa, Bb, g bands. Essentially free of Plasminogen and Fibronectin; traces of von Willebrand factor may be present. Factor XIII is removed employing a modification of the method of McDonah et al, Biochem Biophys Acta 446: 345ff (1976). Cross-linking of a and b chains: complete (in the prescence of Factor XIIIa, 20mM Calcium Chloride, and 5 mM DTT).
• Preparation and Storage: Store at 4 degree C until reconstitution. Following reconstitution aliquot and freeze at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.

Related Product Information for TNXB native protein

Purified native Human Fibrinogen protein

Product Categories/Family for TNXB native protein

Cell Biology; Native Protein

NCBI and Uniprot Product Information

• NCBI GI #: 394794
• NCBI GeneID: 7148
• UniProt Accession #: Q9UE34; P22105
• NCBI Official Full Name: fibrinogen
• NCBI Official Synonym Full Names: tenascin XB
• NCBI Official Symbol: TNXB
• NCBI Official Synonym Symbols: XB; TNX; XBS; EDS3; HXBL; TENX; TN-X; VUR8; TNXB1; TNXB2; TNXBS
• NCBI Protein Information: tenascin-X
• UniProt Protein Name: Fibrinogen
• UniProt Entry Name: Q9UE34_HUMAN