WB (Western Blot)
( Western Blot using anti-OX40L antibody rat muscle (lane 2), rat bladder (lane 3), human breast tumour (lane 4) and human thyroid tumour (lane 5) samples were resolved on a 10% SDS PAGE gel and blots probed with as well as bands corresponding to dimers and other multimers.)
CD40L recombinant antibody
Anti-CD40L [hu5c8 (Ruplizumab)]
Gene Names
CD40LG; IGM; IMD3; TRAP; gp39; CD154; CD40L; HIGM1; T-BAM; TNFSF5; hCD40L
Reactivity
Human
Applications
Western Blot, Flow Cytometry, Functional Assay
Purity
Protein A Affinity Purified
Synonyms
CD40L; N/A; Anti-CD40L [hu5c8 (Ruplizumab)]; CD40 ligand; tumour necrosis factor ligand superfamily member 5; TNFSF5; CD154; tumour necrosis factor related activation protein; TRAP; CD40L recombinant antibody
Reactivity
Human
Isotype
Human IgG1, kappa
Clone Number
hu5c8 (Ruplizumab)
Specificity
The antibody binds to CD40L with an IC50 of 0.845 ug/ml.
Purity/Purification
Protein A Affinity Purified
Sequence Length
261
Applicable Applications for CD40L recombinant antibody
WB (Western Blot), FCM/FACS (Flow Cytometry), Blocking
Buffer Composition
PBS only with 0.02% Proclin 300.
Immunogen
Human CD40L
Chimeric Use Statement
NOT FOR THERAPEUTIC USE - This is a research-grade biosimilar.
Note on publication
Describes the role of CD40-CD40L interaction in immune responses and pathologies. Also describes the generation of humanized monoclonal antibodies against CD40L and the use of a crystal, structure to determine its binding .
Preparation and Storage
Store at 4 degree C for up to 3 months. For longer storage, aliquot and store at -20 degree C.
WB (Western Blot)
( Western Blot using anti-OX40L antibody rat muscle (lane 2), rat bladder (lane 3), human breast tumour (lane 4) and human thyroid tumour (lane 5) samples were resolved on a 10% SDS PAGE gel and blots probed with as well as bands corresponding to dimers and other multimers.)
WB (Western Blot)
( Western Blot using anti-OX40L antibody rat muscle (lane 2), rat bladder (lane 3), human breast tumour (lane 4) and human thyroid tumour (lane 5) samples were resolved on a 10% SDS PAGE gel and blots probed with as well as bands corresponding to dimers and other multimers.)
Related Product Information for CD40L recombinant antibody
Recombinant monoclonal antibody to CD40L. Manufactured using a Recombinant Platform with variable regions (i.e. specificity) from the hybridoma hu5c8 (Ruplizumab). NOT FOR THERAPEUTIC USE - This is a research-grade biosimilar.
Product Categories/Family for CD40L recombinant antibody
References
Karpusas et al. Structure of CD40 Ligand in Complex with the Fab Fragment of a Neutralizing Humanized Antibody Structure. 2001 Apr 4; 9(4):321-9. PMID:11525169
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
UniProt Accession #
NCBI Official Full Name
CD40 ligand
NCBI Official Synonym Full Names
CD40 ligand
NCBI Official Symbol
CD40LG
NCBI Official Synonym Symbols
IGM; IMD3; TRAP; gp39; CD154; CD40L; HIGM1; T-BAM; TNFSF5; hCD40L
NCBI Protein Information
CD40 ligand
UniProt Protein Name
CD40 ligand
UniProt Gene Name
CD40LG
UniProt Synonym Gene Names
CD40L; TNFSF5; TRAP; CD40-L; TRAP
UniProt Entry Name
CD40L_HUMAN
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Product Notes
The CD40L cd40lg (Catalog #AAA71953) is a Recombinant Antibody and is intended for research purposes only. The product is available for immediate purchase. The Anti-CD40L [hu5c8 (Ruplizumab)] reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CD40L can be used in a range of immunoassay formats including, but not limited to, WB (Western Blot), FCM/FACS (Flow Cytometry), Blocking. Researchers should empirically determine the suitability of the CD40L cd40lg for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CD40L, Recombinant Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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