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Beta-2 Microglobulin (B2M) Protein | B2M protein

Beta-2 Microglobulin (B2M)

Purity
>95% (SDS-PAGE)
Synonyms
Beta-2 Microglobulin (B2M); N/A; B2M; BMG; B2M protein
Ordering
Host
Human Urine
Purity/Purification
>95% (SDS-PAGE)
Form/Format
Lyophilized from 0.02 M ammonium bicarbonate pH 7.2 with 150 mM sodium chloride, 1 mM EDTA, 2% mannitol and 0.09% sodium azide.
Source
Urine of renal failure patients
B2M Content
0.14 mg B2M/mg solid
Protein
0.25 mg protein/mg solid (Biuret)
CAS Number
9066-69-7
Handling Information
Reconsitution Advice: Reconstitute in the vial provided and centrifuge briefly to ensure complete recovery.
Handling: Handle as a potentially hazardous substance.
Preparation and Storage
2-8 degree C
Storage Note: protect from moisture
Related Product Information for B2M protein
Serum beta-2 Microglobulin, an endogenous marker for renal function, has been shown to be an independent predictor of mortality in older adults.

The characteristics of B2M make it useful as a tumor marker for some blood cell cancers, for detecting kidney damage, and for distinguishing between glomerular and tubular disorders of the kidney. It is not test for a specific disease, but it gives the doctor additional information about someone's likely prognosis and about the health of their kidneys.

Human b-2 Microglobulin (B2MG) is an 11.8 kD protein identical to the light chain of the HLA-A, -B, and –C antigen. B2MG is expressed on nucleated cells, and is found at low levels in the serum and urine of normal individuals. B2MG concentrations are increased in inflammatory diseases, some viral diseases, renal dysfunction, and autoimmune diseases. A number of publications are available which explain the interpretation of serum levels in assessing the status of individuals with various clinical conditions.

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Product Notes

The B2M (Catalog #AAA44874) is a Protein produced from Human Urine and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Beta-2 Microglobulin (B2M), Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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