IL-4 recombinant protein
Human IL-4 protein
Gene Names
IL4; BSF1; IL-4; BCGF1; BSF-1; BCGF-1
Purity
>95 % as determined by SDS-PAGE
Synonyms
IL-4; N/A; Human IL-4 protein; IL4; IL-4B_cell stimulatory factor 1; B cell growth factor 1; BCGF1; BCGF-1; interleukin 4; binetrakin; BCDF; B-cell stimulatory factor 1; BSF1; BSF-1; IL4E12; interleukin-4; Lymphocyte stimulatory factor 1; MGC79403; pitrakinra; IL-4 recombinant protein
Host
HEK293 Cells
Purity/Purification
>95 % as determined by SDS-PAGE
Form/Format
Lyophilized from sterile PBS, pH7.4.
Protein Length
The recombinant Human IL-4 protein consists of 133 amino acids and has a predicted molecular mass of 15.4kDa. The apparent molecular mass of the Human IL-4 protein is approximately 18kDa in SDS-PAGE under reducing conditions.
Reconstitution
Use the buffer we provided to reconstitute the lyophilized Human IL-4 protein
Endotoxin
< 1 EU per ug of the protein as determined by the LAL method
Usage Notes
Always centrifuge tubes before opening. It is recommended to reconstitute the lyophilized Human IL-4 protein using the buffer we provided not less than 100 ug/mL, which can then be further diluted to other aqueous solutions.
Preparation and Storage
Lyophilized Human IL-4 proteinshould be stored desiccated below -20 degree C. Upon reconstitution, the protein should be Store at 4 degree C between 2-7 days and for future use below -20 degree C. For long term storage it is recommended to add a carrier protein (0.129% HSA or BSA). Please prevent freeze-thaw cycles.
Related Product Information for IL-4 recombinant protein
Background: Interleukin-4(IL-4), an anti-inflammatory cytokine, plays significant role in pathogenesis of various diseases such as asthma, tumors, and HIV infections. IL-4 is firstly identified as a T cell-derived growth factor for B cells. IL-4 can mediate important pro-inflammatory functions in asthma, including T helper cell type 2 lymphocyte differentiation, induction of IgE production, up-regulation of IgE receptors, expression of vascular cell-adhesion molecule 1, promotion of eosinophil transmigration into the lungs, inhibition of T-lymphocyte apoptosis, and mucus hypersecretion. The role of IL-4 in the pathogenesis of asthma is supported by identification of polymorphisms linked to asthma in the IL-4 gene promoter and proteins involved in IL-4 signaling.
Product Categories/Family for IL-4 recombinant protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
NCBI Official Full Name
interleukin-4 isoform 1
NCBI Official Synonym Full Names
interleukin 4
NCBI Official Symbol
IL4
NCBI Official Synonym Symbols
BSF1; IL-4; BCGF1; BSF-1; BCGF-1
NCBI Protein Information
interleukin-4; binetrakin; pitrakinra; B cell growth factor 1; B_cell stimulatory factor 1; lymphocyte stimulatory factor 1
UniProt Protein Name
Interleukin-4
UniProt Gene Name
IL4
UniProt Synonym Gene Names
IL-4; BSF-1
UniProt Entry Name
IL4_HUMAN
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Product Notes
The IL-4 il4 (Catalog #AAA332527) is a Recombinant Protein produced from HEK293 Cells and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "IL-4, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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