HDAC2 active protein
HDAC2 (full-length) (human), (recombinant)
Purity
Partially purified by single-step affinity chromatography and gel filtration
Synonyms
HDAC2; N/A; HDAC2 (full-length) (human), (recombinant); HDAC2 active protein
Host
Insect cells
Purity/Purification
Partially purified by single-step affinity chromatography and gel filtration
Form/Format
Liquid. In 50mM TRIS, pH8.0, 138 mM NaCl and 10% glycerol
Source
Produced in insect cells. Produced in a baculovirus expression system
Sequence
HDAC2 from human cDNA. Sequence is identical to residues 1-582 at Genbank accession# NM_00157.2
Specific Activity
>0.5 U/ug. One U=1 pmol/min at 37 degree C, 100 uM FLUOR DE LYS - SIRT1 substrate (p53K(Ac)-382 fluorogenic substrate)
Note
The enzyme is stable on ice for the time typically required to set up an experiment (30 min-60 min) but may lose activity with prolonged storage on ice. It is recommended that thawing and dilution of the enzyme be done within as short a time as possible before start of the assay. The remaining, unused, undiluted enzyme should be refrozen quickly. For example, snap freezing in a dry/ice ethanol bath or liquid nitrogen. Freezing and storage of diluted enzyme is not recommended
Dry Ice Shipment
Extra charge fee may add to your shipping cost as dry ice is required to ship this product.
Preparation and Storage
For long term storage, store at -80 degree C
Shipping: Shipped on Dry Ice
Shipping: Shipped on Dry Ice
Related Product Information for HDAC2 active protein
HDAC2, like the highly homologous HDAC1, is a class I HDAC first identified as a human homolog of the yeast histone deacetylase Rpd3. HDAC2 found, along with HDAC1 in the Sin3, NuRD. In contrast to class II HDACs, which repress cardiac hypertrophy, HDAC2 activity is required for the cardiac hypertrophic response.
Product Categories/Family for HDAC2 active protein
NCBI and Uniprot Product Information
UniProt Accession #
Molecular Weight
~66kDa
UniProt Protein Name
Histone deacetylase 2
UniProt Gene Name
HDAC2
UniProt Synonym Gene Names
HD2
UniProt Entry Name
HDAC2_HUMAN
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Product Notes
The HDAC2 hdac2 (Catalog #AAA77050) is an Active Protein produced from Insect cells and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "HDAC2, Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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