SDS-PAGE
Cytokeratin Fragment Antigen 21-1 (CYFRA21-1) Recombinant Protein | CYFRA21-1 recombinant protein
Recombinant Human Cytokeratin Fragment Antigen 21-1 (CYFRA21-1) Protein
Gene Names
KRT19; K19; CK19; K1CS
Purity
> 85 % as determined by SDS-PAGE.
Synonyms
Cytokeratin Fragment Antigen 21-1 (CYFRA21-1); N/A; Recombinant Human Cytokeratin Fragment Antigen 21-1 (CYFRA21-1) Protein; K1C19_HUMAN; Keratin, type I cytoskeletal 19; Cytokeratin-19; CK-19; Keratin-19; K19.; CYFRA21-1 recombinant protein
Host
E. coli
Purity/Purification
> 85 % as determined by SDS-PAGE.
Form/Format
58 mM NaHa2PO4, 17 mM NaHa2PO4, 68 mM NaCl, 300 mM Imidazole, pH 8.0, Trehalose (5-8%) and mannitol (5-8%) protectants were added before lyophilization.
Concentration
0.4 mg/mL (varies by lot)
Sequence Positions
80-400
Sequence
EKLTMQNLNDRLASYLDKVRALEAANGELEVKIRDWYQKQGPGPSRDYSHYYTTIQDLRDKILGATIENSRIVLQIDNARLAADDFRTKFETEQALRMSVEADINGLRRVLDELTLARTDLEMQIEGLKEELAYLKKNHEEEISTLRGQVGGQVSVEVDSAPGTDLAKILSDMRSQYEVMAEQNRKDAEAWFTSRTEELNREVAGHTEQLQMSRSEVTDLRRTLQGLEIELQSQLSMKAALEDTLAETEARFGAQLAHIQALISGIEAQLGDVRADSERQNQEYQRLMDIKSRLEQEIATYRSLLEGQEDHYNNLSASKVL
Source
Human
Usage
CYFRA21-1 Protein - Centrifuge the standard vial at 6000-10000rpm for 30s.
Protein Residues
N-terminal GST
Preparation and Storage
Store it under sterile conditions at -20°C upon receipt. Recommend to aliquot the protein into smaller quantities for optimal storage.
Avoid repeated freeze-thaw cycles.
Stability: The recombinant protein is stable for up to 6 months from date of receipt at -80°C.
Avoid repeated freeze-thaw cycles.
Stability: The recombinant protein is stable for up to 6 months from date of receipt at -80°C.
SDS-PAGE
SDS-PAGE
Related Product Information for CYFRA21-1 recombinant protein
Cytokeratin19 Fragment Antigen 21-1(CYFRA21-1) belongs to a family of 20 related polypeptides that are constituents of the intermediate filaments of epithelial cells. Of these CK19 is the most frequently expressed cytokeratin endometrial cancer. CYFRA21-1 is a common tumor marker of lung cancer, non-small-cell cancer, small cell carcinoma and squamous cell carcinoma. For breast cancer, CYFRA21-1 may be comparable to the sensitivity and specificity of CA153. Measured jointly with any of the tumor markers as CEA, SCCA, NSE, can increase the sensitivity. Other as bladder cancer, nasopharyngeal cancer, ovarian cancer, gastrointestinal cancer, and also have certain positive rate. CYFRA21-1 in hepatitis, pancreatitis, pneumonia, benign prostatic hyperplasia may also be increased.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
Predicted MW: 62 kDa
Observed MW: 62 kDa
Observed MW: 62 kDa
NCBI Official Full Name
keratin, type I cytoskeletal 19
NCBI Official Synonym Full Names
keratin 19
NCBI Official Symbol
KRT19
NCBI Official Synonym Symbols
K19; CK19; K1CS
NCBI Protein Information
keratin, type I cytoskeletal 19
UniProt Protein Name
Keratin, type I cytoskeletal 19
UniProt Gene Name
KRT19
UniProt Synonym Gene Names
CK-19; K19
UniProt Entry Name
K1C19_HUMAN
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Product Notes
The CYFRA21-1 krt19 (Catalog #AAA13292) is a Recombinant Protein produced from E. coli and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 80-400. The amino acid sequence is listed below: EKLTMQNLND RLASYLDKVR ALEAANGELE VKIRDWYQKQ GPGPSRDYSH YYTTIQDLRD KILGATIENS RIVLQIDNAR LAADDFRTKF ETEQALRMSV EADINGLRRV LDELTLARTD LEMQIEGLKE ELAYLKKNHE EEISTLRGQV GGQVSVEVDS APGTDLAKIL SDMRSQYEVM AEQNRKDAEA WFTSRTEELN REVAGHTEQL QMSRSEVTDL RRTLQGLEIE LQSQLSMKAA LEDTLAETEA RFGAQLAHIQ ALISGIEAQL GDVRADSERQ NQEYQRLMDI KSRLEQEIAT YRSLLEGQED HYNNLSASKV L. It is sometimes possible for the material contained within the vial of "Cytokeratin Fragment Antigen 21-1 (CYFRA21-1), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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