LRRC15 recombinant protein

LRRC15 Protein, Human, Recombinant (ECD, His Tag)

Cat. Num. AAA258036

• Gene Names: LRRC15; LIB
• Purity: >95% as determined by SDS-PAGE
• Synonyms: LRRC15; N/A; LRRC15 Protein, Human, Recombinant (ECD, His Tag); Human LRRC15 Protein (ECD, His Tag); LIB Protein, Human; leucine rich repeat containing 15; LRRC15 recombinant protein

• Host: HEK293 Cells
• Purity/Purification: >95% as determined by SDS-PAGE
• Form/Format: Lyophilized from sterile PBS, pH7.4, 5% Trehalose, 5% Mannitol, 0.01% Tween-80
• Sequence: Met1-Gly538

• Species: Human
• Endotoxin: <1.0EU per ug protein as determined by the LAL method.
• Predicted N Terminal: Tyr 22
• Tag: C-His
• Protein Construction: A DNA sequence encoding the human LRRC15 (NP_570843.2)(Met1-Gly538) was expressed with a polyhistidine tag at the C-terminus.
• Reconstitution: It is recommended that sterile water (400ul) be added to the vial to prepare a stock solution of 0.25mg/mL. Concentration is measured by UV.
• Preparation and Storage: Samples are stable for twelve months from date of receipt at -20 degree C to -80 degree C. Store it under sterile conditions at -20 degree C to -80 degree C upon receipt. It is recommended that the protein be aliquoted into smaller quantities for optimal storage. Avoid repeated freeze-thaw cycles.

SDS-PAGE

Related Product Information for LRRC15 recombinant protein

Background: LRRC15 (Leucine-Rich Repeat Containing 15) is a Protein Coding gene. 2 alternatively spliced human isoforms have been reported. The tumor antigen 15-leucine-rich repeat-containing membrane protein (LRRC15) is a transmembrane protein demonstrated to play important roles in cancer. LRRC15 is highly expressed in multiple solid tumor indications with limited normal tissue expression. It was expressed on stromal fibroblasts in many solid tumors (e.g., breast, head, and neck, lung, pancreatic) as well as directly on a subset of cancer cells of mesenchymal origin (e.g., sarcoma, melanoma, glioblastoma). The tumor antigen LRRC15, which is frequently overexpressed in multiple tumor types, as a repressor of cell death due to adenoviral p53.

NCBI and Uniprot Product Information

• NCBI GI #: 288541297
• NCBI GeneID: 131578
• NCBI Accession #: NP_570843.2
• NCBI GenBank Nucleotide #: NM_130830.4
• Molecular Weight: The recombinant human LRRC15 consists of 528 amino acids and predicts a molecular mass of 59.2 kDa. As a result of glycosylation, it migrates as an approximately 62.88 kDa band in SDS-PAGE under reducing conditions.
• NCBI Official Full Name: leucine-rich repeat-containing protein 15 isoform b
• NCBI Official Synonym Full Names: leucine rich repeat containing 15
• NCBI Official Symbol: LRRC15
• NCBI Official Synonym Symbols: LIB
• NCBI Protein Information: leucine-rich repeat-containing protein 15; hLib; leucine-rich repeat protein induced by beta amyloid; leucine-rich repeat protein induced by beta-amyloid homolog