Bioactivity
(Measured by its binding ability in a functional ELISA. Immobilized GH1 at 1 ?g/ml can bind human GHR, the EC50 of human GHR protein is 24.96-33.39 ng/ml.)
Growth hormone receptor (GHR) Active Protein | GHR active protein
Recombinant Human Growth hormone receptor (GHR), partial (Active)
Gene Names
GHR; GHBP
Purity
Greater than 90% as determined by SDS-PAGE.
Synonyms
Growth hormone receptor (GHR); N/A; Recombinant Human Growth hormone receptor (GHR), partial (Active); Somatotropin receptor; Serum-binding protein; GHR active protein
Host
Mammalian cell
Purity/Purification
Greater than 90% as determined by SDS-PAGE.
Form/Format
Lyophilized powder
Lyophilized from a 0.2 um filtered PBS, 6% Trehalose, pH 7.4
Lyophilized from a 0.2 um filtered PBS, 6% Trehalose, pH 7.4
Sequence Positions
27-264aa; Partial
Sequence
AILSRAPWSLQSVNPGLKTNSSKEPKFTKCRSPERETFSCHWTDEVHHGTKNLGPIQLFYTRRNTQEWTQEWKECPDYVSAGENSCYFNSSFTSIWIPYCIKLTSNGGTVDEKCFSVDEIVQPDPPIALNWTLLNVSLTGIHADIQVRWEAPRNADIQKGWMVLEYELQYKEVNETKWKMMDPILTTSVPVYSLKVDKEYEVRVRSKQRNSGNYGEFSEVLYVTLPQMSQFTCEEDFY$
Species
Homo sapiens (Human)
Tag
C-terminal hFc-tagged
Endotoxin
Less than 1.0 EU/ug as determined by LAL method.
Research Area
Cancer
Biological Activity
1. Measured by its binding ability in a functional ELISA. Immobilized GH1 at 1 ug/ml can bind human GHR, the EC50 of human GHR protein is 24.96-33.39 ng/ml. 2. Human GH1 protein his/myc tag captured on COOH chip can bind Human GHR protein Fc tag with an affinity constant of 6.1 nM as detected by LSPR Assay.
Preparation and Storage
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 degree C/-80 degree C. The shelf life of lyophilized form is 12 months at -20 degree C/-80 degree C.
Repeated freezing and thawing is not recommended. Store working aliquots at 4 degree C for up to one week.
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL. We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20 degree C/-80 degree C. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Repeated freezing and thawing is not recommended. Store working aliquots at 4 degree C for up to one week.
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL. We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20 degree C/-80 degree C. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Bioactivity
(Measured by its binding ability in a functional ELISA. Immobilized GH1 at 1 ?g/ml can bind human GHR, the EC50 of human GHR protein is 24.96-33.39 ng/ml.)
Bioactivity
(Measured by its binding ability in a functional ELISA. Immobilized GH1 at 1 ?g/ml can bind human GHR, the EC50 of human GHR protein is 24.96-33.39 ng/ml.)
SDS-PAGE
((Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.)
SDS-PAGE
((Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.)
Related Product Information for GHR active protein
Receptor for pituitary gland growth hormone involved in regulating postnatal body growth.
Product Categories/Family for GHR active protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
71,500 Da
NCBI Official Full Name
growth hormone receptor isoform 1
NCBI Official Synonym Full Names
growth hormone receptor
NCBI Official Symbol
GHR
NCBI Official Synonym Symbols
GHBP
NCBI Protein Information
growth hormone receptor; GH receptor; serum binding protein; somatotropin receptor; growth hormone binding protein
UniProt Protein Name
Growth hormone receptor
UniProt Gene Name
GHR
UniProt Synonym Gene Names
GH receptor; GH-binding protein; GHBP
UniProt Entry Name
GHR_HUMAN
Similar Products
Product Notes
The GHR ghr (Catalog #AAA279212) is an Active Protein produced from Mammalian cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 27-264aa; Partial. The amino acid sequence is listed below: AILSRAPWSL QSVNPGLKTN SSKEPKFTKC RSPERETFSC HWTDEVHHGT KNLGPIQLFY TRRNTQEWTQ EWKECPDYVS AGENSCYFNS SFTSIWIPYC IKLTSNGGTV DEKCFSVDEI VQPDPPIALN WTLLNVSLTG IHADIQVRWE APRNADIQKG WMVLEYELQY KEVNETKWKM MDPILTTSVP VYSLKVDKEY EVRVRSKQRN SGNYGEFSEV LYVTLPQMSQ FTCEEDFY$. It is sometimes possible for the material contained within the vial of "Growth hormone receptor (GHR), Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.