Application Data
Tau/TAU441 recombinant protein
Human Tau/TAU441 Protein (isoform 2N4R, His Tag)
Gene Names
MAPT; TAU; MSTD; PPND; DDPAC; MAPTL; MTBT1; MTBT2; FTDP-17
Purity
≥ 95 % as determined by SDS-PAGE.≥ 95 % as determined by SEC-HPLC
Synonyms
Tau/TAU441; N/A; Human Tau/TAU441 Protein (isoform 2N4R, His Tag); microtubule-associated protein tau; DDPAC Protein, Human; FTDP-17 Protein, Human; MAPT Protein, Human; MAPTL Protein, Human; MSTD Protein, Human; MTBT1 Protein, Human; MTBT2 Protein, Human; PPND Protein, Human; PPP1R103 Protein, Human; TAU Protein, Human; Tau/TAU441 recombinant protein
Host
E coli
Purity/Purification
≥ 95 % as determined by SDS-PAGE.
≥ 95 % as determined by SEC-HPLC
≥ 95 % as determined by SEC-HPLC
Form/Format
Lyophilized from sterile 50 mM Tris, 150 mM NaCl, 1 mM TCEP, 1 mM EDTA, pH 7, 5% Trehalose, 5% Mannitol, 0.01% Tween-80.
Source
E. coli-derived Human Tau / TAU441 Protein (isoform 2N4R, His Tag) Ala2-Leu441, Accession # P10636-8
Species
Predicted N Terminal
Met
Endotoxin
<1.0 EU per ug of the protein as determined by the LAL method
Protein Construction
A DNA sequence encoding the Human Tau/TAU441 (P10636-8)(Ala2-Leu441) was expressed, with a polyhistidine tag at the N-terminus.
Reconstitution
Reconstituted with sterile deionized water to 0.25 mg/mL.
Preparation and Storage
Samples are stable for up to twelve months from date of receipt at -20 degree C to -80 degree C. Store it under sterile conditions at -20 degree C to -80 degree C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Application Data
Application Data
References
Harada A, et al. (1994) Altered microtubule organization in small-calibre axons of mice lacking tau protein. Nature. 369(6480):488-91.
Weingarten MD, et al. (1975) A protein factor essential for microtubule assembly. Proc Natl Acad Sci. 72(5):1858-62.
Goedert M, et al. (1989) Multiple isoforms of human microtubule-associated protein tau: sequences and localization in neurofibrillary tangles of Alzheimer's disease. Neuron. 3(4): 519-26.
Weingarten MD, et al. (1975) A protein factor essential for microtubule assembly. Proc Natl Acad Sci. 72(5):1858-62.
Goedert M, et al. (1989) Multiple isoforms of human microtubule-associated protein tau: sequences and localization in neurofibrillary tangles of Alzheimer's disease. Neuron. 3(4): 519-26.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
46.68 kDa
The recombinant Human Tau / TAU441 consists of 447 amino acids and predicts a molecular mass of 46.68 kDa
The recombinant Human Tau / TAU441 consists of 447 amino acids and predicts a molecular mass of 46.68 kDa
NCBI Official Full Name
microtubule-associated protein tau isoform 6
NCBI Official Synonym Full Names
microtubule-associated protein tau
NCBI Official Symbol
MAPT
NCBI Official Synonym Symbols
TAU; MSTD; PPND; DDPAC; MAPTL; MTBT1; MTBT2; FTDP-17
NCBI Protein Information
microtubule-associated protein tau; PHF-tau; paired helical filament-tau; neurofibrillary tangle protein; microtubule-associated protein tau, isoform 4; G protein beta1/gamma2 subunit-interacting factor 1
UniProt Protein Name
Microtubule-associated protein tau
UniProt Gene Name
MAPT
UniProt Synonym Gene Names
MAPTL; MTBT1; TAU; PHF-tau
UniProt Entry Name
TAU_HUMAN
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Product Notes
The Tau/TAU441 mapt (Catalog #AAA259220) is a Recombinant Protein produced from E coli and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Tau/TAU441, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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