FCM/FACS (Flow Cytometry)
(Figure 3. Flow cytometry data of serially titrated Rabbit anti-4-1BB monoclonal antibody (clone: DM67) on Expi 293 cell line transfected with human 4-1BB. The Y-axis represents the mean fluorescence intensity (MFI) while the X-axis represents the concentration of IgG used.)
Rabbit anti-Human 4-1BB Monoclonal Antibody | anti-4-1BB antibody
Anti-4-1BB antibody (DM67), Rabbit mAb
Gene Names
TNFRSF9; ILA; 4-1BB; CD137; CDw137
Reactivity
Human
Applications
Flow Cytometry, Functional Assay, ELISA
Purity
Purified from cell culture supernatant by affinity chromatography
Synonyms
4-1BB, Antibody; Anti-4-1BB antibody (DM67), Rabbit mAb; TNFRSF9; 4-1BB; CD137; CDw137; ILA; anti-4-1BB antibody
Host
Rabbit
Reactivity
Human
Clonality
Monoclonal
Isotype
Rabbit IgG
Clone Number
DM67
Purity/Purification
Purified from cell culture supernatant by affinity chromatography
Form/Format
Lyophilized from sterile PBS, pH7.4. Normally 5%-8% trehalose is added as protectants before lyophilization. 0.1% Procline 300
Applicable Applications for anti-4-1BB antibody
FCM/FACS (Flow Cytometry), ELISA
Immunogen
Recombinant human 4-1BB (Leu24-Gln186) produced by using human HEK293 cells
Reconstitution
Reconstitute with deionized water
Preparation and Storage
Store at -20 degree C for 12 months (Avoid repeated freezing and thawing)
FCM/FACS (Flow Cytometry)
(Figure 3. Flow cytometry data of serially titrated Rabbit anti-4-1BB monoclonal antibody (clone: DM67) on Expi 293 cell line transfected with human 4-1BB. The Y-axis represents the mean fluorescence intensity (MFI) while the X-axis represents the concentration of IgG used.)
FCM/FACS (Flow Cytometry)
(Figure 3. Flow cytometry data of serially titrated Rabbit anti-4-1BB monoclonal antibody (clone: DM67) on Expi 293 cell line transfected with human 4-1BB. The Y-axis represents the mean fluorescence intensity (MFI) while the X-axis represents the concentration of IgG used.)
FCM/FACS (Flow Cytometry)
(Figure 3. Flow cytometry data of serially titrated Rabbit anti-4-1BB monoclonal antibody (clone: DM67) on Expi 293 cell line transfected with human 4-1BB. The Y-axis represents the mean fluorescence intensity (MFI) while the X-axis represents the concentration of IgG used.)
FCM/FACS (Flow Cytometry)
(Figure 3. Flow cytometry data of serially titrated Rabbit anti-4-1BB monoclonal antibody (clone: DM67) on Expi 293 cell line transfected with human 4-1BB. The Y-axis represents the mean fluorescence intensity (MFI) while the X-axis represents the concentration of IgG used.)
ELISA
(Figure 3. Flow cytometry data of serially titrated Rabbit anti-4-1BB monoclonal antibody (clone: DM67) on Expi 293 cell line transfected with human 4-1BB. The Y-axis represents the mean fluorescence intensity (MFI) while the X-axis represents the concentration of IgG used.)
ELISA
(Figure 3. Flow cytometry data of serially titrated Rabbit anti-4-1BB monoclonal antibody (clone: DM67) on Expi 293 cell line transfected with human 4-1BB. The Y-axis represents the mean fluorescence intensity (MFI) while the X-axis represents the concentration of IgG used.)
Related Product Information for anti-4-1BB antibody
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contributes to the clonal expansion, survival, and development of T cells. It can also induce proliferation in peripheral monocytes, enhance T cell apoptosis induced by TCR/CD3 triggered activation, and regulate CD28 co-stimulation to promote Th1 cell responses. The expression of this receptor is induced by lymphocyte activation. TRAF adaptor proteins have been shown to bind to this receptor and transduce the signals leading to activation of NF-kappaB.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
27,899 Da
NCBI Official Full Name
tumor necrosis factor receptor superfamily member 9
NCBI Official Synonym Full Names
tumor necrosis factor receptor superfamily, member 9
NCBI Official Symbol
TNFRSF9
NCBI Official Synonym Symbols
ILA; 4-1BB; CD137; CDw137
NCBI Protein Information
tumor necrosis factor receptor superfamily member 9; CD137 antigen; T cell antigen ILA; T-cell antigen ILA; 4-1BB ligand receptor; homolog of mouse 4-1BB; receptor protein 4-1BB; T-cell antigen 4-1BB homolog; induced by lymphocyte activation (ILA); interl
UniProt Protein Name
Tumor necrosis factor receptor superfamily member 9
UniProt Gene Name
TNFRSF9
UniProt Synonym Gene Names
CD137; ILA
UniProt Entry Name
TNR9_HUMAN
Similar Products
Product Notes
The 4-1BB tnfrsf9 (Catalog #AAA47415) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-4-1BB antibody (DM67), Rabbit mAb reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's 4-1BB can be used in a range of immunoassay formats including, but not limited to, FCM/FACS (Flow Cytometry), ELISA. Researchers should empirically determine the suitability of the 4-1BB tnfrsf9 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "4-1BB, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.