Application Data
(Detection of ATF4 in neuroblastoma cell line SKN-BE at 10ug/ml: DAPI (blue) nuclear stain, Texas Red F actin stain, ATTO 488 (green) ATF4 stain.)
Mouse Activating Transcription Factor 4 (ATF4) Monoclonal Antibody | anti-ATF4 antibody
Activating Transcription Factor 4 (ATF4) Monoclonal Antibody
Gene Names
ATF4; CREB2; TXREB; CREB-2; TAXREB67
Applications
Immunofluorescence, Immunoblot, Western Blot
Synonyms
Activating Transcription Factor 4 (ATF4), Antibody; Activating Transcription Factor 4 (ATF4) Monoclonal Antibody; anti-ATF4 antibody
Host
Mouse
Clonality
Monoclonal
Isotype
IgG2a
Specificity
This antibody recognizes human and rat ATF4.
Form/Format
100ug (1mg/ml) Protein G-purified antibody in PBS, pH 7.4, 0.1% sodium azide, 50% glycerol.
Sequence Length
351
Applicable Applications for anti-ATF4 antibody
IF (Immunofluorescence), IB (Immunoblot)
Immunogen
Fusion protein corresponding to aa 25-327 of human ATF4. This sequence is 86% identical in rat, 85% identical in mouse, and <50% identical in ATF5.
Preparation and Storage
This product is stable for at least one (1) year at-20 degree C.
Application Data
(Detection of ATF4 in neuroblastoma cell line SKN-BE at 10ug/ml: DAPI (blue) nuclear stain, Texas Red F actin stain, ATTO 488 (green) ATF4 stain.)
Application Data
(Detection of ATF4 in neuroblastoma cell line SKN-BE at 10ug/ml: DAPI (blue) nuclear stain, Texas Red F actin stain, ATTO 488 (green) ATF4 stain.)
Application Data
(Detection of ATF4 in rat brain lysate)
Application Data
(Detection of ATF4 in rat brain lysate)
Related Product Information for anti-ATF4 antibody
ATF4 belongs to the large ATF/CREB family of transcription factors. These proteins bind DNA via their basic region and dimerize via their leucine zipper domain to form a variety of homo-and heterodimers that regulate gene transcription. Two alternative transcripts encoding the same protein have been described. ATF4 transcription factor is also known to play role in osteoblast differentiation. Terminal osteoblast differentiation, is significantly inhibited by the inactivation of JNK; JNK inactivation downregulates expression of ATF-4.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
38,590 Da
NCBI Official Full Name
cyclic AMP-dependent transcription factor ATF-4
NCBI Official Synonym Full Names
activating transcription factor 4
NCBI Official Symbol
ATF4
NCBI Official Synonym Symbols
CREB2; TXREB; CREB-2; TAXREB67
NCBI Protein Information
cyclic AMP-dependent transcription factor ATF-4
UniProt Protein Name
Cyclic AMP-dependent transcription factor ATF-4
UniProt Gene Name
ATF4
UniProt Synonym Gene Names
CREB2; TXREB; cAMP-dependent transcription factor ATF-4; CREB-2; cAMP-responsive element-binding protein 2; TaxREB67
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Product Notes
The ATF4 atf4 (Catalog #AAA47885) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's Activating Transcription Factor 4 (ATF4) can be used in a range of immunoassay formats including, but not limited to, IF (Immunofluorescence), IB (Immunoblot). Researchers should empirically determine the suitability of the ATF4 atf4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Activating Transcription Factor 4 (ATF4), Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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