Mouse anti-Human, Mouse AHNAK1 Monoclonal Antibody | anti-AHNAK1 antibody
Anti-AHNAK1 Purified
Gene Names
AHNAK; PM227; AHNAKRS
Reactivity
Human, Mouse
Applications
Immunoprecipitation, Immunocytochemistry, Immunohistochemistry, Western Blot
Purity
Purified by Protein-A Affinity Chromatography
Synonyms
AHNAK1, Antibody; Anti-AHNAK1 Purified; AHNAK1 nucleoprotein; Desmoyokin; anti-AHNAK1 antibody
Host
Mouse
Reactivity
Human, Mouse
Clonality
Monoclonal
Isotype
IgG1
Clone Number
EM-09
Specificity
The mouse monoclonal antibody EM-09 reacts with AHNAK1, a 700 kDa multi-functional adaptor protein expressed mainly in epithelial cell, various types of muscle cells and immune cells.
Purity/Purification
Purified by Protein-A Affinity Chromatography
Form/Format
Phosphate buffered saline (PBS) solution with 15 mM sodium azide
Concentration
1 mg/ml (varies by lot)
Sequence Length
5890
Applicable Applications for anti-AHNAK1 antibody
IP (Immunoprecipitation), ICC (Immunocytochemistry), IHC (Immunohistochemistry), WB (Western Blot)
Immunogen
Bacterially expressed fragment of N-terminal domain of human AHNAK1.
Preparation and Storage
Store at 2-8 degree C.
Related Product Information for anti-AHNAK1 antibody
AHNAK1 (Desmoyokin) is a large (700 kDa) scaffold protein that translocates to the plasma membrane after an increas of extracellular calcium level or upon proteinkinase C activation and regulates extracellular calcium influx mediated by L-type Ca2+ channels. AHNAK1 has been implicated in diverse signal transduction proceses affecting cell differentiation and proliferation. In response to calcium-dependent intercellular contacts AHNAK1 forms multimeric complexes in the plasma membrane, connected with actin and annexin 2/S100A10 assemblies and is thus involved in organization of the plasma membrane architecture. In epithelial cells, AHNAK1 is localized in cytoplasm or is membrane-associated, but in cells of nonepithelial origin AHNAK1 is predominantly nuclear; it has a weak DNA-binding activity and associates with the DNA-ligase IV-XRCC4 complex.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
neuroblast differentiation-associated protein AHNAK isoform 1
NCBI Official Synonym Full Names
AHNAK nucleoprotein
NCBI Official Symbol
AHNAK
NCBI Official Synonym Symbols
PM227; AHNAKRS
NCBI Protein Information
neuroblast differentiation-associated protein AHNAK
UniProt Protein Name
Neuroblast differentiation-associated protein AHNAK
UniProt Gene Name
AHNAK
UniProt Synonym Gene Names
PM227
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Product Notes
The AHNAK1 ahnak (Catalog #AAA128524) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Anti-AHNAK1 Purified reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's AHNAK1 can be used in a range of immunoassay formats including, but not limited to, IP (Immunoprecipitation), ICC (Immunocytochemistry), IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the AHNAK1 ahnak for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "AHNAK1, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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