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product-image-AAA62972_WB6.jpg WB (Western Blot) (Western Blot Analysis of Human Stomach, Mouse Stomach and Rat Stomach tissue lysates using ALDH1A1 Mouse Monoclonal Antibody (ALDH1A1/1381).)

Mouse anti-Human, Rat ALDH1A1 (Aldehyde Dehydrogenase 1A1) Monoclonal Antibody | anti-ALDH1A1 antibody

ALDH1A1 (Aldehyde Dehydrogenase 1A1)

Gene Names
ALDH1A1; ALDC; ALDH1; HEL-9; HEL12; PUMB1; ALDH11; RALDH1; ALDH-E1; HEL-S-53e
Reactivity
Human, Rat
Applications
Immunohistochemistry, Western Blot
Synonyms
ALDH1A1 (Aldehyde Dehydrogenase 1A1), Antibody; ALDH1A1 (Aldehyde Dehydrogenase 1A1); Acetaldehyde dehydrogenase 1; AHD2; ALDC; Aldehyde dehydrogenase 1 soluble; Aldehyde dehydrogenase 1A1; Aldehyde dehydrogenase family 1 member A1; ALDH-E1; ALDH1; ALDH1A1; epididymis luminal protein 12; epididymis luminal protein 9; epididymis secretory sperm binding protein Li 53e; HEL-S-53e; PUMB1; RALDH1; Retinal dehydrogenase 1; anti-ALDH1A1 antibody
Ordering
Host
Mouse
Reactivity
Human, Rat
Clonality
Monoclonal
Isotype
IgG1 / Kappa
Clone Number
ALDH1A1/1381
Specificity
ALDH1A1 belongs to the ALDH enzymes, a family of evolutionarily conserved enzymes comprised of 19 isoforms that are localized in the cytoplasm, mitochondria or nucleus. ALDH1A1 is predominantly expressed in the epithelium of testis, brain, eye, liver, kidney, as well as neural and hematopoietic stem cells. Reportedly, high ALDH1A1 expression is found in solitary fibrous tumor (SFT) and hemangiopericytoma (HPC), compared to meningiomas and synovial sarcomas. In combination with CD34, ALDH1A1 may be useful for the differentiation among SFT, HPC, meningioma, and synovial sarcoma.
Form/Format
1.0 mg/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS
Sequence Length
501
Applicable Applications for anti-ALDH1A1 antibody
IHC (Immunohistochemistry), WB (Western Blot)
Immunogen
Recombinant fragment (around aa 315-434) of human ALDH1A1 protein (exact sequence is proprietary).
Cellular Localization
Axon, Cell projection, Cytoplasm, Cytosol
Positive Control
HepG2 or A549 cells. Human and Rat stomach, Colon or Testicular Carcinoma., K562, Liver, Lung, Brain
Research Areas
Signal Transduction
Preparation and Storage
Antibody without azide - store at -20 to -80°C.

WB (Western Blot)

(Western Blot Analysis of Human Stomach, Mouse Stomach and Rat Stomach tissue lysates using ALDH1A1 Mouse Monoclonal Antibody (ALDH1A1/1381).)

product-image-AAA62972_WB6.jpg WB (Western Blot) (Western Blot Analysis of Human Stomach, Mouse Stomach and Rat Stomach tissue lysates using ALDH1A1 Mouse Monoclonal Antibody (ALDH1A1/1381).)

WB (Western Blot)

(Western Blot Analysis of Human Brain tissue lysate using ALDH1A1 Mouse Monoclonal Antibody (ALDH1A1/1381).)

product-image-AAA62972_WB7.jpg WB (Western Blot) (Western Blot Analysis of Human Brain tissue lysate using ALDH1A1 Mouse Monoclonal Antibody (ALDH1A1/1381).)

SDS-PAGE

(SDS-PAGE Analysis of Purified ALDH1A1 Mouse Monoclonal Antibody (ALDH1A1/1381). Confirmation of Integrity and Purity of Antibody.)

product-image-AAA62972_SDS_PAGE8.jpg SDS-PAGE (SDS-PAGE Analysis of Purified ALDH1A1 Mouse Monoclonal Antibody (ALDH1A1/1381). Confirmation of Integrity and Purity of Antibody.)

WB (Western Blot)

(Western Blot Analysis of human Liver tissue lysate using ALDH1A1 Mouse Monoclonal Antibody (ALDH1A1/1381).)

product-image-AAA62972_WB10.jpg WB (Western Blot) (Western Blot Analysis of human Liver tissue lysate using ALDH1A1 Mouse Monoclonal Antibody (ALDH1A1/1381).)

WB (Western Blot)

(Western Blot of K562 and Lung Lysate using ALDH1A1 Monoclonal Antibody (ALDH1A1/1381).)

product-image-AAA62972_WB11.jpg WB (Western Blot) (Western Blot of K562 and Lung Lysate using ALDH1A1 Monoclonal Antibody (ALDH1A1/1381).)

IHC (Immunohiostchemistry)

(Formalin-fixed, paraffin-embedded Human Testicular Carcinoma stained with ALDH1A1 Monoclonal Antibody (ALDH1A1/1381).)

product-image-AAA62972_IHC13.jpg IHC (Immunohiostchemistry) (Formalin-fixed, paraffin-embedded Human Testicular Carcinoma stained with ALDH1A1 Monoclonal Antibody (ALDH1A1/1381).)

IHC (Immunohistochemistry)

(Formalin-fixed, paraffin-embedded Human Colon Carcinoma stained with ALDH1A1 Monoclonal Antibody (ALDH1A1/1381).)

product-image-AAA62972_IHC15.jpg IHC (Immunohistochemistry) (Formalin-fixed, paraffin-embedded Human Colon Carcinoma stained with ALDH1A1 Monoclonal Antibody (ALDH1A1/1381).)
References
Xu J, Muller S, Nannapaneni S, Pan L, Wang Y, Peng X, Wang D, Tighiouart M, Chen Z, Saba NF, Beitler JJ, Shin DM, Chen ZG. Comparison of quantum dot technology with conventional immunohistochemistry in examining aldehyde dehydrogenase 1A1 as a potential biomarker for lymph node metastasis of head and neck cancer. Eur J Cancer. 2012 Jul; 48(11):1682-91.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
216
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
56kDa
NCBI Official Full Name
retinal dehydrogenase 1
NCBI Official Synonym Full Names
aldehyde dehydrogenase 1 family member A1
NCBI Official Symbol
ALDH1A1
NCBI Official Synonym Symbols
ALDC; ALDH1; HEL-9; HEL12; PUMB1; ALDH11; RALDH1; ALDH-E1; HEL-S-53e
NCBI Protein Information
retinal dehydrogenase 1
UniProt Protein Name
Retinal dehydrogenase 1
UniProt Gene Name
ALDH1A1
UniProt Synonym Gene Names
RALDH 1Curated; RalDH1Curated

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Product Notes

The ALDH1A1 aldh1a1 (Catalog #AAA62972) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The ALDH1A1 (Aldehyde Dehydrogenase 1A1) reacts with Human, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's ALDH1A1 (Aldehyde Dehydrogenase 1A1) can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the ALDH1A1 aldh1a1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ALDH1A1 (Aldehyde Dehydrogenase 1A1), Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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