IHC (Immunohiostchemistry)
(Immunohistochemical analysis of ALK-1 in human lymphoma using ALK-1 antibody (Clone #: ABM43C4) at 1 ug/ml.)
Mouse anti-Human ALK-1 Monoclonal Antibody | anti-ALK-1 antibody
ALK-1 Monoclonal Antibody
Gene Names
ACVRL1; HHT; ALK1; HHT2; ORW2; SKR3; ALK-1; TSR-I; ACVRLK1
Reactivity
Human
Applications
Immunohistochemistry, Western Blot
Purity
Protein G Chromatography
Synonyms
ALK-1, Antibody; ALK-1 Monoclonal Antibody; ACVRL1, ACVRLK1, ALK1; anti-ALK-1 antibody
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
Mouse IgG1, Kappa
Clone Number
ABM43C4
Purity/Purification
Protein G Chromatography
Form/Format
25 μg in 50 μl/100 μg in 200 μl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.
Concentration
0.5 mg/ml, 200 ul (varies by lot)
Sequence Length
503
Applicable Applications for anti-ALK-1 antibody
IHC (Immunohistochemistry), WB (Western Blot)
Antigen
ALK-1
Immunogen
A partial length recombinant ALK-1 protein (amino acids 310-503) was used as the immunogen for this antibody
Preparation and Storage
Store antibody at 4 degree C, stable for 6 months. For long-term storage, store at -20 degree C. Avoid repeated freeze and thaw cycles. Expire 1 year from date of purchase.
IHC (Immunohiostchemistry)
(Immunohistochemical analysis of ALK-1 in human lymphoma using ALK-1 antibody (Clone #: ABM43C4) at 1 ug/ml.)
IHC (Immunohiostchemistry)
(Immunohistochemical analysis of ALK-1 in human lymphoma using ALK-1 antibody (Clone #: ABM43C4) at 1 ug/ml.)
WB (Western Blot)
(Expression analysis of ALK-1. Anti- ALK-1 antibody (Clone #: ABM43C4) was tested at 0.5 ug/ml on partial recombinant protein.)
WB (Western Blot)
(Expression analysis of ALK-1. Anti- ALK-1 antibody (Clone #: ABM43C4) was tested at 0.5 ug/ml on partial recombinant protein.)
Related Product Information for anti-ALK-1 antibody
ALK-1 or Activin receptor-like kinase-1 is a type I cell surface receptor for the TGF-beta (transforming growth factor-beta) super family of proteins. It is expressed predominantly in endothelial cells with moderate expression in smooth muscle cells, myofibroblast, hepatic stellate cells, chondrocytes, monocytes, myoblasts, macrophages and fibroblasts. ALK-1 plays a pivotal role in vascular remodelling and angiogenesis. More specifically its key function is in arterial/venous differentiation during embryonic vascular development. Mutations in ALK-1 gene (12q11-14) causes HHT2 (Hereditary Haemorrhagic Telangiectasia type 2), an autosomal dominant multisystem vascular dysplasia caused by a haploinsufficiency mechanism.
Product Categories/Family for anti-ALK-1 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
NCBI Official Full Name
serine/threonine-protein kinase receptor R3
NCBI Official Synonym Full Names
activin A receptor type II-like 1
NCBI Official Symbol
ACVRL1
NCBI Official Synonym Symbols
HHT; ALK1; HHT2; ORW2; SKR3; ALK-1; TSR-I; ACVRLK1
NCBI Protein Information
serine/threonine-protein kinase receptor R3
UniProt Protein Name
Serine/threonine-protein kinase receptor R3
UniProt Gene Name
ACVRL1
UniProt Synonym Gene Names
ACVRLK1; ALK1; SKR3; ALK-1; TSR-I
UniProt Entry Name
ACVL1_HUMAN
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Product Notes
The ALK-1 acvrl1 (Catalog #AAA78235) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The ALK-1 Monoclonal Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's ALK-1 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the ALK-1 acvrl1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ALK-1, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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